Experiments are reported in which it was shown that the calcium, inorganic phosphorus, cholesterol, and lecithin in the blood of normal rabbits were influenced by inoculation with a malignant tumor (4).

Animals in which death was due to tumor gave results on which the following conclusions are based:

1. A marked increase in inorganic phosphorus of blood serum and cholesterol of whole blood followed inoculation.

2. The ratios of cholesterol to calcium and lecithin to calcium increased in trend, while the calcium to inorganic phosphorus, lecithin to cholesterol, and lecithin to inorganic phosphorus ratios showed a marked decrease in trend.

3. The r cholesterol-lecithin were all negative.

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