A method of measuring the rate of excretion of urea, in terms of the normal, as presented in a preceding paper, has been applied to the study of diseased conditions and of the action of drugs. Simultaneous observations on chloride excretion have been made by comparing the concentration of chlorides actually found in the plasma with the theoretical amount, calculated from the rate of excretion. Observations made in this way have been found applicable to the study of various diseased conditions.

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