ENDOCRINES AND THEIR RELATION TO INFLUENZA VIRUS INFECTION

Kalter , Seymour S.; Smolin , Harold J.; McElhaney , Jane M.; Tepperman , Jay

doi:10.1084/jem.93.6.529

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Article| June 01 1951

ENDOCRINES AND THEIR RELATION TO INFLUENZA VIRUS INFECTION

Seymour S. Kalter,

Seymour S. Kalter

From the Departments of Bacteriology and Parasitology, and Pharmacology, State University of New York Medical College, and the Virus Laboratory, Bureau of Laboratories, Syracuse

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Harold J. Smolin,

Harold J. Smolin

From the Departments of Bacteriology and Parasitology, and Pharmacology, State University of New York Medical College, and the Virus Laboratory, Bureau of Laboratories, Syracuse

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Jane M. McElhaney,

Jane M. McElhaney

From the Departments of Bacteriology and Parasitology, and Pharmacology, State University of New York Medical College, and the Virus Laboratory, Bureau of Laboratories, Syracuse

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Jay Tepperman

From the Departments of Bacteriology and Parasitology, and Pharmacology, State University of New York Medical College, and the Virus Laboratory, Bureau of Laboratories, Syracuse

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Author and Article Information

Seymour S. Kalter

From the Departments of Bacteriology and Parasitology, and Pharmacology, State University of New York Medical College, and the Virus Laboratory, Bureau of Laboratories, Syracuse

Harold J. Smolin

From the Departments of Bacteriology and Parasitology, and Pharmacology, State University of New York Medical College, and the Virus Laboratory, Bureau of Laboratories, Syracuse

Jane M. McElhaney

From the Departments of Bacteriology and Parasitology, and Pharmacology, State University of New York Medical College, and the Virus Laboratory, Bureau of Laboratories, Syracuse

Jay Tepperman

From the Departments of Bacteriology and Parasitology, and Pharmacology, State University of New York Medical College, and the Virus Laboratory, Bureau of Laboratories, Syracuse

Received: January 31 1951

Online ISSN: 1540-9538

Print ISSN: 0022-1007

Copyright, 1951, by The Rockefeller Institute for Medical Research New York

1951

J Exp Med (1951) 93 (6): 529–538.

https://doi.org/10.1084/jem.93.6.529

Treatment with testosterone increases proliferation of influenza virus as well as protein anabolism. A relative lack of testosterone caused by castration is associated with a diminished rate of virus growth. When protein catabolism is increased by ACTH or cortisone, the rate of virus proliferation decreases. These results suggest the existence of a correlation between alterations of protein metabolism and virus proliferation.

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Copyright, 1951, by The Rockefeller Institute for Medical Research New York

1951

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ENDOCRINES AND THEIR RELATION TO INFLUENZA VIRUS INFECTION

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