Studies have been made on a possible protective action of cortin in the prevention of anaphylactic shock induced by crystallized egg albumin.
Of sixteen control guinea pigs only two survived.
Sixteen of thirty-three cortin-treated animals received hormone at the optimum period of from 2 to 6 hours before the shocking dose. Nine survived and two others showed some protection. In groups treated at other time intervals the evidence of protection is inconclusive.
2 weeks after the first test the cortin-treated survivors succumbed to a second antigen dose, which was not preceded by cortical extract.
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Copyright, 1935, by The Rockefeller Institute for Medical Research New York
1935
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