The effector memory T (TEM) cells that battle these viruses at infection sites develop from a pool of CD4+ central memory (TCM) cells that are stored in secondary lymphoid organs. Although the virus infects both types of cells simultaneously, TEM cells are the first casualties. This early depletion of TEM cells is not completely devastating; the TCM population quickly cranks out more TEM cells. But this...
The Rockefeller University Press
2007
The Rockefeller University Press
2007
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