PANCREATIC TRANSPLANTATIONS IN THE SPLEEN

Pratt , Joseph H.; Murphy , Fred T.

doi:10.1084/jem.17.3.252

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Article| March 01 1913

PANCREATIC TRANSPLANTATIONS IN THE SPLEEN

Joseph H. Pratt,

Joseph H. Pratt

From the Laboratory of the Theory and Practice of Physic, Harvard University, Boston.

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Fred T. Murphy

From the Laboratory of the Theory and Practice of Physic, Harvard University, Boston.

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Author and Article Information

Joseph H. Pratt

From the Laboratory of the Theory and Practice of Physic, Harvard University, Boston.

Fred T. Murphy

From the Laboratory of the Theory and Practice of Physic, Harvard University, Boston.

Received: November 21 1912

Online ISSN: 1540-9538

Print ISSN: 0022-1007

Copyright, 1913, by The Rockefeller Institute for Medical Research New York

1913

J Exp Med (1913) 17 (3): 252–272.

https://doi.org/10.1084/jem.17.3.252

Pancreatic tissue implanted in the spleen and separated from its original vascular and nervous connections can live and functionate for months. A small nodule of pancreatic tissue composed of acini without demonstrable islands of Langerhans prevented the development of diabetes. Death occurred 187 days after the extirpation of the pancreas.

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Copyright, 1913, by The Rockefeller Institute for Medical Research New York

1913

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