INDUCTION OF ARGINASE ACTIVITY WITH THE SHOPE PAPILLOMA VIRUS IN TISSUE CULTURE CELLS FROM AN ARGININEMIC PATIENT

Rogers , Stanfield; Lowenthal , A.; Terheggen , H. G.; Columbo , J. P.

doi:10.1084/jem.137.4.1091

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Brief Definitive Report| April 01 1973

INDUCTION OF ARGINASE ACTIVITY WITH THE SHOPE PAPILLOMA VIRUS IN TISSUE CULTURE CELLS FROM AN ARGININEMIC PATIENT

Stanfield Rogers,

Stanfield Rogers

From the Biology Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37830, Foundation Born-Bunge, Antwerp, Belgium, Kinderkrankenhaus, Cologne, West Germany, and Inselspital Bern, Chemisches Zentrallabor, Bern, Switzerland

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A. Lowenthal,

A. Lowenthal

From the Biology Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37830, Foundation Born-Bunge, Antwerp, Belgium, Kinderkrankenhaus, Cologne, West Germany, and Inselspital Bern, Chemisches Zentrallabor, Bern, Switzerland

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H. G. Terheggen,

H. G. Terheggen

From the Biology Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37830, Foundation Born-Bunge, Antwerp, Belgium, Kinderkrankenhaus, Cologne, West Germany, and Inselspital Bern, Chemisches Zentrallabor, Bern, Switzerland

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J. P. Columbo

From the Biology Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37830, Foundation Born-Bunge, Antwerp, Belgium, Kinderkrankenhaus, Cologne, West Germany, and Inselspital Bern, Chemisches Zentrallabor, Bern, Switzerland

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Author and Article Information

Stanfield Rogers

From the Biology Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37830, Foundation Born-Bunge, Antwerp, Belgium, Kinderkrankenhaus, Cologne, West Germany, and Inselspital Bern, Chemisches Zentrallabor, Bern, Switzerland

A. Lowenthal

From the Biology Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37830, Foundation Born-Bunge, Antwerp, Belgium, Kinderkrankenhaus, Cologne, West Germany, and Inselspital Bern, Chemisches Zentrallabor, Bern, Switzerland

H. G. Terheggen

From the Biology Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37830, Foundation Born-Bunge, Antwerp, Belgium, Kinderkrankenhaus, Cologne, West Germany, and Inselspital Bern, Chemisches Zentrallabor, Bern, Switzerland

J. P. Columbo

From the Biology Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37830, Foundation Born-Bunge, Antwerp, Belgium, Kinderkrankenhaus, Cologne, West Germany, and Inselspital Bern, Chemisches Zentrallabor, Bern, Switzerland

Received: October 20 1972

Online ISSN: 1540-9538

Print ISSN: 0022-1007

1973

J Exp Med (1973) 137 (4): 1091–1096.

https://doi.org/10.1084/jem.137.4.1091

Inoculation of the Shope virus in tissue cultures of human fibroblasts from a patient with a deficiency of the enzyme arginase results in an induction of arginase activity, apparently virus coded.

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