SUPPRESSION OF ALLERGIC UVEITIS BY 6-MERCAPTOPURINE

Wirostko , E.; Halbert , S. P.

doi:10.1084/jem.116.5.653

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Article| November 01 1962

SUPPRESSION OF ALLERGIC UVEITIS BY 6-MERCAPTOPURINE

E. Wirostko,

E. Wirostko

From the Department of Ophthalmology, College of Physicians and Surgeons, Columbia University, New York

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S. P. Halbert

From the Department of Ophthalmology, College of Physicians and Surgeons, Columbia University, New York

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Author and Article Information

E. Wirostko

From the Department of Ophthalmology, College of Physicians and Surgeons, Columbia University, New York

S. P. Halbert

From the Department of Ophthalmology, College of Physicians and Surgeons, Columbia University, New York

Received: July 02 1962

Online ISSN: 1540-9538

Print ISSN: 0022-1007

1962

J Exp Med (1962) 116 (5): 653–664.

https://doi.org/10.1084/jem.116.5.653

Experimental uveitis in rabbits was induced by single intraocular antigen injection. Treatment with 6-MP for 14 days suppressed the allergic inflammation and antibody response. A good correlation was demonstrated between the degree of uveitis and the antibody titer.

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