Sun et al. highlight eTACs as a key component in the group of RORγt⁺ antigen-presenting cells acting in the induction of RORγt⁺ pTregs specific to food antigens, while implicating DCs in the generation of RORγt⁻ pTregs.

Laura Mackay is a professor and Immunology Theme Leader at the Doherty Institute at the University of Melbourne. Her lab investigates memory T cells, including their development, the role tissue-resident memory T cells play in cancer, autoimmune diseases, and barrier immunity, as well as ways in which these cells may be used therapeutically to treat various pathologies.

Influenza virus remains a public health burden for which recommendations encourage annual vaccination. However, some studies have suggested repeat annual vaccination may have negative effects on influenza virus immunity. This review analyzes immunological mechanisms that may result in reduced effectiveness of annual influenza virus vaccines.