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Journal Articles

Insights into retinal disease and non-tubulin glutamylation from a RPGR–TTLL5 complex structure

James H. Park, Richard J.Y. Liu, Xun Sun, Kishore K. Mahalingan, Suja Hiriyanna, Tiansen Li, Antonina Roll-Mecak
Journal: Journal of Cell Biology
J Cell Biol (2026) 225 (6): e202508020.
https://doi.org/10.1083/jcb.202508020
Published: 03 April 2026
View article titled, Insights into retinal disease and non-tubulin glutamylation from a RPGR–TTLL5 complex structure
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Includes: Supplementary data
Journal Articles

The cytoskeleton contributes to abnormal genome–lamina interactions in LMNA-deficient cardiomyocytes

Kaitlyn M. Shen, Emily J. Shields, Vasia Barka, Ashley Karnay, Leonie M. Kurzlechner, Jennifer D. Yang, Qiaohong Wang, Benjamin W. Lee, Carmen Suay-Corredera, Son C. Nguyen, Eric F. Joyce, Kenneth B. Margulies, Benjamin L. Prosser, Parisha P. Shah, Rajan Jain
Journal: Journal of Cell Biology
J Cell Biol (2026) 225 (5): e202506137.
https://doi.org/10.1083/jcb.202506137
Published: 27 March 2026
View article titled, The cytoskeleton contributes to abnormal genome–lamina interactions in LMNA-deficient cardiomyocytes
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Includes: Supplementary data
Journal Articles

GRIPAP1 is an endosomal tethering factor mediating platelet α-granule biogenesis

Andrea L. Ambrosio, Hallie P. Febvre, Gabrielle H. Schusler, Santiago M. Di Pietro
Journal: Journal of Cell Biology
J Cell Biol (2026) 225 (4): e202507149.
https://doi.org/10.1083/jcb.202507149
Published: 03 February 2026
View article titled, GRIPAP1 is an endosomal tethering factor mediating platelet α-granule biogenesis
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Includes: Supplementary data
Journal Articles

RCC1 depletion drives protein transport defects and rupture in micronuclei

In Special Collection:
Cancer Cell Biology 2026
Molly G. Zych, Maya Contreras, Anna E. Mammel, Emily M. Hatch
Journal: Journal of Cell Biology
J Cell Biol (2026) 225 (4): e202510133.
https://doi.org/10.1083/jcb.202510133
Published: 03 February 2026
View article titled, RCC1 depletion drives protein transport defects and rupture in micronuclei
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Includes: Supplementary data
Journal Articles

Maspardin/SPG21 controls lysosome motility and TFEB phosphorylation through RAB7 positioning

Thomas Jacqmin, Florentine Gilis, Martine Albert, Jean-François Gaussin, Michel Jadot, Marielle Boonen
Journal: Journal of Cell Biology
J Cell Biol (2025) 225 (2): e202501135.
https://doi.org/10.1083/jcb.202501135
Published: 16 December 2025
View article titled, Maspardin/SPG21 controls lysosome motility and TFEB phosphorylation through RAB7 positioning
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Includes: Supplementary data
Journal Articles

DUX4-induced HSATII RNA accumulation drives protein aggregation, impacting RNA processing pathways

Tessa Arends, Sean R. Bennett, Stephen J. Tapscott
Journal: Journal of Cell Biology
J Cell Biol (2025) 225 (2): e202501129.
https://doi.org/10.1083/jcb.202501129
Published: 02 December 2025
View article titled, DUX4-induced HSATII RNA accumulation drives protein aggregation, impacting RNA processing pathways
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Includes: Supplementary data
Journal Articles

Tepsin and AP4 mediate transport from the trans-Golgi to the plant-like vacuole in toxoplasma

Janessa Grech, Abhishek Prakash Shinde, Javier Periz, Mirko Singer, Simon Gras, Ignasi Forné, Andreas Klingl, Joel B. Dacks, Elena Jiménez-Ruiz, Markus Meissner
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (12): e202312109.
https://doi.org/10.1083/jcb.202312109
Published: 13 October 2025
View article titled, Tepsin and AP4 mediate transport from the trans-Golgi to the plant-like vacuole in toxoplasma
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Includes: Supplementary data
Journal Articles

Vesicle adaptors in malaria parasites show conservation and flexibility of protein sorting machinery

José Cubillán-Marín, Ulrike Fröhlke, Gala Ramón-Zamorano, Sheila Mainye, Joëlle Paolo Mesén-Ramírez, Guilherme B. Farias, Katharina Höhn, Tim-Wolf Gilberger, Richárd Bártfai, Tobias Spielmann
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (12): e202504062.
https://doi.org/10.1083/jcb.202504062
Published: 13 October 2025
View article titled, Vesicle adaptors in malaria parasites show conservation and flexibility of protein sorting machinery
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Includes: Supplementary data
Journal Articles

JIP4 and RILPL1 utilize opposing motor force to dynamically regulate lysosomal tubulation

Luis Bonet-Ponce, Tsion Tegicho, Nuria Fernandez-Martinez, Irene A. Rozenberg, Mia Ashriem, Alexandra Beilina, Jillian H. Kluss, Yan Li, Mark R. Cookson
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (11): e202404018.
https://doi.org/10.1083/jcb.202404018
Published: 24 September 2025
View article titled, JIP4 and RILPL1 utilize opposing motor force to dynamically regulate lysosomal tubulation
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Includes: Supplementary data
Journal Articles

Dominant-negative isoform of TDP-43 is regulated by ALS-linked RNA-binding proteins

Minami Hasegawa-Ogawa, Asako Onda-Ohto, Takumasa Nakajo, Arisa Funabashi, Ayane Ohya, Ryota Yazaki, Hirotaka James Okano
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (10): e202406097.
https://doi.org/10.1083/jcb.202406097
Published: 08 August 2025
View article titled, Dominant-negative isoform of TDP-43 is regulated by ALS-linked RNA-binding proteins
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Includes: Supplementary data
Journal Articles

SOD1 is delivered to lysosomes via autophagy to maintain lysosomal function and integrity

In Special Collection:
Autophagy 2026
Yanzhe Zheng, Meng Li, Xuelin Chen, Ze Zheng, Zixuan Chen, Ruilin Tian, Yan G. Zhao
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (10): e202501007.
https://doi.org/10.1083/jcb.202501007
Published: 07 August 2025
View article titled, SOD1 is delivered to lysosomes via autophagy to maintain lysosomal function and integrity
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Includes: Supplementary data
Journal Articles

FUT8-mediated core fucosylation stabilizes TMEM67 to promote ciliogenesis

Difei Wang, Qingchao Li, Zhenqi Yu, Junkui Zhao, Mingzheng Hu, Xiaoshan Geng, Xinzhe Liu, Siyang Zhao, Ting Song, Min Liu, Dengwen Li, Huijie Zhao, Jun Zhou
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (10): e202412224.
https://doi.org/10.1083/jcb.202412224
Published: 29 July 2025
View article titled, FUT8-mediated core fucosylation stabilizes TMEM67 to promote ciliogenesis
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Includes: Supplementary data
Journal Articles

New insights into lipid droplet breakdown in alcohol-associated hepatic steatosis

Chen Zhang, Wen-Xing Ding
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (8): e202506103.
https://doi.org/10.1083/jcb.202506103
Published: 29 July 2025
View article titled, New insights into lipid droplet breakdown in alcohol-associated hepatic steatosis
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Journal Articles

ALDH9A1 deficiency as a source of endogenous DNA damage that requires repair by the Fanconi anemia pathway

In Special Collection:
Cancer Cell Biology 2026
Moonjung Jung, Jungwoo Kim, Yeji Park, Isaac Ilyashov, Fan Yang, Haruna B. Choijilsuren, Danielle Keahi, Jordan A. Durmaz, Habin Bea, Audrey M. Goldfarb, Mia D. Stein, Claudia Wong, Ryan R. White, Sunandini Sridhar, Raymond Noonan, Tom F. Wiley, Thomas S. Carroll, Francis P. Lach, Sangmoo Jeong, Ileana C. Miranda, Agata Smogorzewska
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (7): e202407141.
https://doi.org/10.1083/jcb.202407141
Published: 20 June 2025
View article titled, ALDH9A1 deficiency as a source of endogenous DNA damage that requires repair by the Fanconi anemia pathway
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Includes: Supplementary data
Journal Articles

Visualizing nuclear pore complex plasticity with pan-expansion microscopy

Kimberly J. Morgan, Emma Carley, Alyssa N. Coyne, Jeffrey D. Rothstein, C. Patrick Lusk, Megan C. King
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (9): e202409120.
https://doi.org/10.1083/jcb.202409120
Published: 12 June 2025
View article titled, Visualizing nuclear pore complex plasticity with pan-expansion microscopy
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Includes: Supplementary data
Journal Articles

The primary cilium as a gatekeeper of FGFR2 function

Raman Kaushik, Raj K. Ladher
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (7): e202505022.
https://doi.org/10.1083/jcb.202505022
Published: 12 June 2025
View article titled, The primary cilium as a gatekeeper of FGFR2 function
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Journal Articles

The reaction mechanism for glycolysis side product degradation by Parkinson’s disease–linked DJ-1

Aiko Watanabe, Shizuka Ogiwara, Mirei Saito, Masaki Mishima, Masahiro Yamashina, Ryuichiro Ishitani, Yutaka Ito, Keiji Tanaka, Fumika Koyano, Koji Yamano, Hidetaka Kosako, Yoshitaka Moriwaki, Noriyuki Matsuda
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (8): e202411078.
https://doi.org/10.1083/jcb.202411078
Published: 04 June 2025
View article titled, The reaction mechanism for glycolysis side product degradation by Parkinson’s disease–linked DJ-1
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Includes: Supplementary data
Journal Articles

A multifunction murine Col4a1 allele reveals potential gene therapy parameters for Gould syndrome

Mao Mao, Yoshihiro Ishikawa, Cassandre Labelle-Dumais, Xiaowei Wang, Yien-Ming Kuo, Uma B. Gaffney, Megan E. Smith, Carlie N. Abdala, Matthew D. Lebedev, William J. Paradee, Douglas B. Gould
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (6): e202409153.
https://doi.org/10.1083/jcb.202409153
Published: 25 April 2025
View article titled, A multifunction murine Col4a1 allele reveals potential gene therapy parameters for Gould syndrome
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Includes: Supplementary data
Journal Articles

A collagen IV fluorophore knock-in toolkit reveals trimer diversity in C. elegans basement membranes

Sandhya Srinivasan, William Ramos-Lewis, Mychel R.P.T. Morais, Qiuyi Chi, Adam W.J. Soh, Emily Williams, Rachel Lennon, David R. Sherwood
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (6): e202412118.
https://doi.org/10.1083/jcb.202412118
Published: 18 March 2025
View article titled, A collagen IV fluorophore knock-in toolkit reveals trimer diversity in C. elegans basement membranes
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Includes: Supplementary data
Journal Articles

TANGO2 is an acyl-CoA binding protein

Agustin Leonardo Lujan, Ombretta Foresti, Jose Wojnacki, Gonzalo Bigliani, Nathalie Brouwers, Maria Jesus Pena, Stefania Androulaki, Tomomi Hashidate-Yoshida, Maria Kalyukina, Sergey S. Novoselov, Hideo Shindou, Vivek Malhotra
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (5): e202410001.
https://doi.org/10.1083/jcb.202410001
Published: 27 February 2025
View article titled, TANGO2 is an acyl-CoA binding protein
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Includes: Supplementary data

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