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Journal Articles

Cullin-3 adaptor SHKBP1 inhibits SQSTM1/p62 oligomerization and Keap1 sequestration

Lin Luan, Xiaofu Cao, Zijun Xia, Shivanshi Vaid, Manuel D. Leonetti, Jeremy M. Baskin

J Cell Biol (2026) 225 (4): e202501207.

https://doi.org/10.1083/jcb.202501207

Published: 06 February 2026

View article titled, Cullin-3 adaptor SHKBP1 inhibits SQSTM1/p62 oligomerization and Keap1 sequestration

Includes: Supplementary data

Journal Articles

Drosophila Abi maintains blood cell homeostasis by promoting clathrin-mediated endocytosis of Notch

Hyun Gwan Park, Seunghwan Song, Joohyung Kim, Seungbok Lee

J Cell Biol (2025) 225 (3): e202505091.

https://doi.org/10.1083/jcb.202505091

Published: 26 December 2025

View article titled, Drosophila Abi maintains blood cell homeostasis by promoting clathrin-mediated endocytosis of Notch

Includes: Supplementary data

Journal Articles

A crucial step toward understanding tip growth in plants

Ivan Radin

J Cell Biol (2025) 225 (1): e202510221.

https://doi.org/10.1083/jcb.202510221

Published: 17 December 2025

View article titled, A crucial step toward understanding tip growth in plants

Journal Articles

Loss of ErbB3 redirects Integrin β1 from early endosomal recycling to secretion in extracellular vesicles

Dorival Mendes Rodrigues-Junior, Ana Rosa Sáez-Ibáñez, Takeshi Terabayashi, Nina Daubel, Taija Mäkinen, Olof Idevall-Hagren, Aristidis Moustakas, Ingvar Ferby

J Cell Biol (2025) 225 (1): e202501255.

https://doi.org/10.1083/jcb.202501255

Published: 05 December 2025

View article titled, Loss of ErbB3 redirects Integrin β1 from early endosomal recycling to secretion in extracellular vesicles

Journal Articles

Phosphatidylserine exposure and annexin A5 weaken the actin cortex in osteoclast fusion

Evgenia Leikina, Andrey K. Tsaturyan, Kamran Melikov, Jarred M. Whitlock, Jared Cunanan, Morgan Roegner, Griffin Katz, Michael M. Kozlov, Leonid V. Chernomordik

J Cell Biol (2025) 225 (2): e202508055.

https://doi.org/10.1083/jcb.202508055

Published: 02 December 2025

View article titled, Phosphatidylserine exposure and annexin A5 weaken the actin cortex in osteoclast fusion

Includes: Supplementary data

Journal Articles

A new probe illuminates endo-lysosomal Ca²⁺ measurements: A role for vesicular IP₃ receptors?

Anthony J. Morgan

J Cell Biol (2025) 224 (12): e202511020.

https://doi.org/10.1083/jcb.202511020

Published: 17 November 2025

View article titled, A new probe illuminates endo-lysosomal Ca2+ measurements: A role for vesicular IP3 receptors?

Journal Articles

Reevaluating the roles of PPARs and nuclear receptors in human peroxisome biology

Fred D. Mast, Richard A. Rachubinski, John D. Aitchison

J Cell Biol (2025) 224 (12): e202506162.

https://doi.org/10.1083/jcb.202506162

Published: 11 November 2025

View article titled, Reevaluating the roles of PPARs and nuclear receptors in human peroxisome biology

Journal Articles

Direct measurements of luminal Ca²⁺ with endo-lysosomal GFP-aequorin reveal functional IP₃ receptors

Belén Calvo, Patricia Torres-Vidal, Alba Delrio-Lorenzo, Carla Rodriguez, Francisco J. Aulestia, Jonathan Rojo-Ruiz, Beatriz Callejo, Bridget M. McVeigh, Marco Keller, Christian Grimm, Viola Oorschot, Vera Moiseenkova-Bell, David I. Yule, Javier Garcia-Sancho, Sandip Patel, M. Teresa Alonso

J Cell Biol (2025) 224 (12): e202410094.

https://doi.org/10.1083/jcb.202410094

Published: 07 November 2025

View article titled, Direct measurements of luminal Ca2+ with endo-lysosomal GFP-aequorin reveal functional IP3 receptors

Includes: Supplementary data

Journal Articles

RTF1 enhances CLK occupancy and histone methylation at key circadian clock pacemaker gene loci

Xu Liu, Ya Huang, Jiajia Fang, Xianli He, Yue Zhou, Wei Luan, Xianhui Liu, Yong Zhang

J Cell Biol (2025) 224 (12): e202501221.

https://doi.org/10.1083/jcb.202501221

Published: 04 November 2025

View article titled, RTF1 enhances CLK occupancy and histone methylation at key circadian clock pacemaker gene loci

Includes: Supplementary data

Journal Articles

B4GALT1 and Wntless collaborate to block LRP5/6 translocation from Golgi to cell surface

Xinyang Li, Yue Hua, Jiahui Wang, Mengxiao Wu, Yu Pan, Jiyong Wang, Xiaoqing Gan

J Cell Biol (2025) 224 (12): e202501170.

https://doi.org/10.1083/jcb.202501170

Published: 03 November 2025

View article titled, B4GALT1 and Wntless collaborate to block LRP5/6 translocation from Golgi to cell surface

Includes: Supplementary data

Journal Articles

Moesin strikes an “Actin”g balance to regulate osteoclast fusion and activity

Marwa Zeyad, Yousef Abu-Amer

J Cell Biol (2025) 224 (11): e202509068.

https://doi.org/10.1083/jcb.202509068

Published: 27 October 2025

View article titled, Moesin strikes an “Actin”g balance to regulate osteoclast fusion and activity

Journal Articles

TMEM175 does not function as a proton-selective ion channel to prevent lysosomal over-acidification

Erika Riederer, Vedrana Mikusevic, Tuoxian Tang, Lillian Martin, Joseph A. Mindell, Dejian Ren

J Cell Biol (2025) 225 (1): e202501145.

https://doi.org/10.1083/jcb.202501145

Published: 24 October 2025

View article titled, TMEM175 does not function as a proton-selective ion channel to prevent lysosomal over-acidification

Journal Articles

Fibroblasts promote osmotic surveillance by wound-induced unique calcium patterns

László Fazekas, Diána Kaszás, Boldizsár Vámosi, Szimonetta Xénia Tamás, Tamás Szöllősi, Vivien Mihályi, Fabian Gregor Dehne, Klaudia Vágó-Kiss, Nada Mohamed Al-Sheraji, Barnabás Paulovits, Benoit Thomas Roux, Balázs Enyedi

J Cell Biol (2025) 225 (1): e202501165.

https://doi.org/10.1083/jcb.202501165

Published: 22 October 2025

View article titled, Fibroblasts promote osmotic surveillance by wound-induced unique calcium patterns

Journal Articles

IQSEC2/BRAG1 may modulate postsynaptic density assembly through Ca²⁺-induced phase separation

Guanhua Bai, Ruifeng Huang, Xinyue Nan, Mengru Zhuang, Meiling Wu, Yinmiao Lian, Qixu Cai, Honglei Tian, Youming Lu, Hao Li, Mingjie Zhang

J Cell Biol (2025) 224 (12): e202503076.

https://doi.org/10.1083/jcb.202503076

Published: 22 October 2025

View article titled, IQSEC2/BRAG1 may modulate postsynaptic density assembly through Ca2+-induced phase separation

Includes: Supplementary data

Journal Articles

CD47 inhibits phagocytosis through Vav dephosphorylation

Wyatt D. Miller, Andrew Manion, Abhinava K. Mishra, Connor J. Sheedy, Annalise Bond, Brooke M. Gardner, Denise J. Montell, Meghan A. Morrissey

J Cell Biol (2025) 224 (12): e202502206.

https://doi.org/10.1083/jcb.202502206

Published: 16 October 2025

View article titled, CD47 inhibits phagocytosis through Vav dephosphorylation

Includes: Supplementary data

Journal Articles

Target cell adhesion limits macrophage phagocytosis and promotes trogocytosis

Kirstin R. Rollins, Sareen Fiaz, Ishwaree Datta, Meghan A. Morrissey

J Cell Biol (2025) 224 (11): e202502034.

https://doi.org/10.1083/jcb.202502034

Published: 03 October 2025

View article titled, Target cell adhesion limits macrophage phagocytosis and promotes trogocytosis

Includes: Supplementary data

Journal Articles

Vacuolar pH regulates clathrin-mediated endocytosis through TORC1 signaling during replicative aging

Kenneth Gabriel Antenor, Jaime Lee-Dadswell, Natasha Salahshour, Nina Grishchenko, Shaimaa Swaleh, Gurjyot Makhija, Allie Spangaro, Mojca Mattiazzi Usaj

J Cell Biol (2025) 224 (11): e202412064.

https://doi.org/10.1083/jcb.202412064

Published: 24 September 2025

View article titled, Vacuolar pH regulates clathrin-mediated endocytosis through TORC1 signaling during replicative aging

Includes: Supplementary data

Journal Articles

ATG conjugation–dependent/independent mechanisms underlie lysosomal stress–induced TFEB regulation

Shiori Akayama, Takayuki Shima, Tatsuya Kaminishi, Mengying Cui, Jlenia Monfregola, Kohei Nishino, Andrea Ballabio, Hidetaka Kosako, Tamotsu Yoshimori, Shuhei Nakamura

J Cell Biol (2025) 224 (10): e202307079.

https://doi.org/10.1083/jcb.202307079

Published: 29 August 2025

View article titled, ATG conjugation–dependent/independent mechanisms underlie lysosomal stress–induced TFEB regulation

Includes: Supplementary data

Journal Articles

Submembrane liprin-α1 clusters spatially localize insulin granule fusion

Kylie Deng, Kitty Sun, Nicole Hallahan, Wan Jun Gan, Michelle Cielesh, Baharak Mahyad, Melkam A. Kebede, Mark Larance, Peter Thorn

J Cell Biol (2025) 224 (10): e202410210.

https://doi.org/10.1083/jcb.202410210

Published: 28 August 2025

View article titled, Submembrane liprin-α1 clusters spatially localize insulin granule fusion

Includes: Supplementary data

Journal Articles

Identification of organelle-specific autophagy regulators from tandem CRISPR screens

In Special Collection:

The Year in Cell Biology: 2025

Truc T. Losier, Karyn E. King, Maxime W.C. Rousseaux, Ryan C. Russell

J Cell Biol (2025) 224 (10): e202405138.

https://doi.org/10.1083/jcb.202405138

Published: 21 August 2025

View article titled, Identification of organelle-specific autophagy regulators from tandem CRISPR screens

Includes: Supplementary data

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Cullin-3 adaptor SHKBP1 inhibits SQSTM1/p62 oligomerization and Keap1 sequestration

Drosophila Abi maintains blood cell homeostasis by promoting clathrin-mediated endocytosis of Notch

A crucial step toward understanding tip growth in plants

Loss of ErbB3 redirects Integrin β1 from early endosomal recycling to secretion in extracellular vesicles

Phosphatidylserine exposure and annexin A5 weaken the actin cortex in osteoclast fusion

A new probe illuminates endo-lysosomal Ca²⁺ measurements: A role for vesicular IP₃ receptors?

Reevaluating the roles of PPARs and nuclear receptors in human peroxisome biology

Direct measurements of luminal Ca²⁺ with endo-lysosomal GFP-aequorin reveal functional IP₃ receptors

RTF1 enhances CLK occupancy and histone methylation at key circadian clock pacemaker gene loci

B4GALT1 and Wntless collaborate to block LRP5/6 translocation from Golgi to cell surface

Moesin strikes an “Actin”g balance to regulate osteoclast fusion and activity

TMEM175 does not function as a proton-selective ion channel to prevent lysosomal over-acidification

Fibroblasts promote osmotic surveillance by wound-induced unique calcium patterns

IQSEC2/BRAG1 may modulate postsynaptic density assembly through Ca²⁺-induced phase separation

CD47 inhibits phagocytosis through Vav dephosphorylation

Target cell adhesion limits macrophage phagocytosis and promotes trogocytosis

Vacuolar pH regulates clathrin-mediated endocytosis through TORC1 signaling during replicative aging

ATG conjugation–dependent/independent mechanisms underlie lysosomal stress–induced TFEB regulation

Submembrane liprin-α1 clusters spatially localize insulin granule fusion

Identification of organelle-specific autophagy regulators from tandem CRISPR screens

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