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Journal Articles
The Journal of Cell Biology (2020) 219 (2): e201911058.
Published: 24 January 2020
Images
Three discrete actin networks collaborate to create distinct functional reg...
Published: 24 January 2020
Figure 1. Three discrete actin networks collaborate to create distinct functional regions within the canonical “bullseye” IS. The outer ring of the IS (distal supramolecular activation cluster [dSMAC]) corresponds to the lamellipodium of a migrating cell. This region contains a prominent branche... More
Images
TCR deformation translates mechanical forces into biochemical signals  .  (...
Published: 24 January 2020
Figure 2. TCR deformation translates mechanical forces into biochemical signals . (A) In the resting state, ITAM motifs within the cytoplasmic domains of CD3 molecules interact with the inner leaflet of the T cell plasma membrane. (B) Protrusive forces applied by the T cell bring the TCR int... More
Images
Force contributes to T cell activation through several distinct actin struc...
Published: 24 January 2020
Figure 3. Force contributes to T cell activation through several distinct actin structures. (A) Overview of a T cell scanning an APC by migrating on its surface. During this process, discrete actin structures apply force at different areas of the T cell–APC interaction, facilitating T cell acti... More
Journal Articles
The Journal of Cell Biology (2020) 219 (2): e202001006.
Published: 23 January 2020
Journal Articles
The Journal of Cell Biology (2020) 219 (2): e202001048.
Published: 23 January 2020
Journal Articles
The Journal of Cell Biology (2020) 219 (2): e202001060.
Published: 23 January 2020
Images
Schematic of the relationship between putative neuronal glycogen metabolic ...
Published: 23 January 2020
Figure 1. Schematic of the relationship between putative neuronal glycogen metabolic pathways and established glycolytic and oxidative phosphorylation pathways in normal (left) and metabolically stressed (right) neurons. Metabolic stressors can ultimately lead to apoptotic or necrotic cell death... More
Images
Images
RPE-1 cells exposed to transient Polo-like kinase 4 overexpression to induc...
Published: 23 January 2020
RPE-1 cells exposed to transient Polo-like kinase 4 overexpression to induce extra centrosomes in interphase (top) and mitosis (bottom). Cells were stained for microtubules (α-tubulin; cyan), centrioles (centrin2; yellow), and DNA (magenta). Image courtesy of Susana Godinho. More
Images
The laboratory at the Centre for Cancer Cell and Molecular Biology Christma...
Published: 23 January 2020
The laboratory at the Centre for Cancer Cell and Molecular Biology Christmas party, December 2019. Left to right: Judit, Dina, Judith, Bongwhan, Susana, Emily, Sophie, and Sarah. Image courtesy of Susana Godinho. More
Images
A model for pronuclear fusion in the one-cell  C. elegans  embryo.  (A)  A ...
Published: 23 January 2020
Figure 1. A model for pronuclear fusion in the one-cell C. elegans embryo. (A) A cartoon of two pronuclei in the post-fertilized C. elegans embryo (arrow indicates the pronuclear interface). (B) The pronuclear interface at prometaphase, with gray boxes indicating nuclear pore complex–asso... More
Images
Marilyn Farquhar, in her element at Yale.  Photo courtesy of Yale Universit...
Published: 22 January 2020
Figure 1. Marilyn Farquhar, in her element at Yale. Photo courtesy of Yale University School of Medicine. More
Images
Traffic in and out of the Golgi.  (Top) Membrane recycling in secretory cel...
Published: 22 January 2020
Figure 2. Traffic in and out of the Golgi. (Top) Membrane recycling in secretory cells followed by plasma membrane–bound cationized ferritin. Micrograph originally from Farquhar (1978) and reproduced in Farquhar and Palade (1981) . (Bottom) Diagram reproduced from Farquhar and Palade (1981) ... More
Journal Articles
The Journal of Cell Biology (2020) 219 (2): e201807127.
Published: 22 January 2020
Journal Articles
The Journal of Cell Biology (2020) 219 (3): e201904090.
Published: 22 January 2020
Includes: Supplementary data
Journal Articles
The Journal of Cell Biology (2020) 219 (2): e202001010.
Published: 22 January 2020
Journal Articles
The Journal of Cell Biology (2020) 219 (3): e201908142.
Published: 20 January 2020
Journal Articles
The Journal of Cell Biology (2020) 219 (2): e201911139.
Published: 20 January 2020
Images
Model for the role of NuMA1 in AIS assembly.  (a)  In early development, DC...
Published: 20 January 2020
Figure 1. Model for the role of NuMA1 in AIS assembly. (a) In early development, DCX and Lis1 facilitate endocytosis of NF186, thus inhibiting the clustering of Neurofascin on plasma membrane. (b) During AIS assembly, NuMA1 inhibits the interaction of DCX and Lis1, leading to inhibition of en... More