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Richard A. Firtel
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Journal Articles

Both contractile axial and lateral traction force dynamics drive amoeboid cell motility

Effie Bastounis, Ruedi Meili, Begoña Álvarez-González, Joshua Francois, Juan C. del Álamo, Richard A. Firtel, Juan C. Lasheras
Journal: Journal of Cell Biology
J Cell Biol (2014) 204 (6): 1045–1061.
https://doi.org/10.1083/jcb.201307106
Published: 17 March 2014
View articletitled, Both contractile axial and lateral traction force dynamics drive amoeboid cell motility
Open the PDF for Both contractile axial and lateral traction force dynamics drive amoeboid cell motility in another window
Includes: Supplementary data
Journal Articles

Regulation of Rap1 activity by RapGAP1 controls cell adhesion at the front of chemotaxing cells

Taeck J. Jeon, Dai-Jen Lee, Susan Lee, Gerald Weeks, Richard A. Firtel
Journal: Journal of Cell Biology
J Cell Biol (2007) 179 (5): 833–843.
https://doi.org/10.1083/jcb.200705068
Published: 26 November 2007
View articletitled, Regulation of Rap1 activity by RapGAP1 controls cell adhesion at the front of chemotaxing cells
Open the PDF for Regulation of Rap1 activity by RapGAP1 controls cell adhesion at the front of chemotaxing cells in another window
Includes: Supplementary data
Journal Articles

G protein–independent Ras/PI3K/F-actin circuit regulates basic cell motility

Atsuo T. Sasaki, Chris Janetopoulos, Susan Lee, Pascale G. Charest, Kosuke Takeda, Lauren W. Sundheimer, Ruedi Meili, Peter N. Devreotes, Richard A. Firtel
Journal: Journal of Cell Biology
J Cell Biol (2007) 178 (2): 185–191.
https://doi.org/10.1083/jcb.200611138
Published: 16 July 2007
View articletitled, G protein–independent Ras/PI3K/F-actin circuit regulates basic cell motility
Open the PDF for G protein–independent Ras/PI3K/F-actin circuit regulates basic cell motility in another window
Includes: Supplementary data
Journal Articles

Rap1 controls cell adhesion and cell motility through the regulation of myosin II

Taeck J. Jeon, Dai-Jen Lee, Sylvain Merlot, Gerald Weeks, Richard A. Firtel
Journal: Journal of Cell Biology
J Cell Biol (2007) 176 (7): 1021–1033.
https://doi.org/10.1083/jcb.200607072
Published: 19 March 2007
View articletitled, Rap1 controls cell adhesion and cell motility through the regulation of myosin II
Open the PDF for Rap1 controls cell adhesion and cell motility through the regulation of myosin II in another window
Includes: Supplementary data
Journal Articles

Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement

Atsuo T. Sasaki, Cheryl Chun, Kosuke Takeda, Richard A. Firtel
Journal: Journal of Cell Biology
J Cell Biol (2004) 167 (3): 505–518.
https://doi.org/10.1083/jcb.200406177
Published: 08 November 2004
View articletitled, Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement
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Journal Articles

Role of Phosphatidylinositol 3′ Kinase and a Downstream Pleckstrin Homology Domain–Containing Protein in Controlling Chemotaxis inDictyostelium

Satoru Funamoto, Kristina Milan, Ruedi Meili, Richard A. Firtel
Journal: Journal of Cell Biology
J Cell Biol (2001) 153 (4): 795–810.
https://doi.org/10.1083/jcb.153.4.795
Published: 14 May 2001
View articletitled, Role of Phosphatidylinositol 3′ Kinase and a Downstream Pleckstrin Homology Domain–Containing Protein in Controlling Chemotaxis inDictyostelium
Open the PDF for Role of Phosphatidylinositol 3′ Kinase and a Downstream Pleckstrin Homology Domain–Containing Protein in Controlling Chemotaxis inDictyostelium in another window
Journal Articles

Paka, a Putative Pak Family Member, Is Required for Cytokinesis and the Regulation of the Cytoskeleton in Dictyostelium discoideum Cells during Chemotaxis

Chang Y. Chung, Richard A. Firtel
Journal: Journal of Cell Biology
J Cell Biol (1999) 147 (3): 559–576.
https://doi.org/10.1083/jcb.147.3.559
Published: 01 November 1999
View articletitled, Paka, a Putative Pak Family Member, Is Required for Cytokinesis and the Regulation of the Cytoskeleton in Dictyostelium discoideum Cells during Chemotaxis
Open the PDF for Paka, a Putative Pak Family Member, Is Required for Cytokinesis and the Regulation of the Cytoskeleton in Dictyostelium discoideum Cells during Chemotaxis in another window
Journal Articles

Inactivation of Two Dictyostelium discoideum Genes, DdPIK1 and DdPIK2, Encoding Proteins Related to Mammalian Phosphatidylinositide 3-kinases, Results in Defects in Endocytosis, Lysosome to Postlysosome Transport, and Actin Cytoskeleton Organization

Greg Buczynski, Bryon Grove, Anson Nomura, Maurice Kleve, John Bush, Richard A. Firtel, James Cardelli
Journal: Journal of Cell Biology
J Cell Biol (1997) 136 (6): 1271–1286.
https://doi.org/10.1083/jcb.136.6.1271
Published: 24 March 1997
View articletitled, Inactivation of Two Dictyostelium discoideum Genes, DdPIK1 and DdPIK2, Encoding Proteins Related to Mammalian Phosphatidylinositide 3-kinases, Results in Defects in Endocytosis, Lysosome to Postlysosome Transport, and Actin Cytoskeleton Organization
Open the PDF for Inactivation of Two Dictyostelium discoideum Genes, DdPIK1 and DdPIK2, Encoding Proteins Related to Mammalian Phosphatidylinositide 3-kinases, Results in Defects in Endocytosis, Lysosome to Postlysosome Transport, and Actin Cytoskeleton Organization in another window