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Niels Mailand
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Journal Articles

PML mutants from arsenic-resistant patients reveal SUMO1-TOPORS and SUMO2/3-RNF4 degradation pathways

Ellis G. Jaffray, Michael H. Tatham, Barbara Mojsa, Anna Plechanovová, Alejandro Rojas-Fernandez, Julio C.Y. Liu, Niels Mailand, Adel F.M. Ibrahim, Graeme Ball, Iain M. Porter, Ronald T. Hay
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (6): e202407133.
https://doi.org/10.1083/jcb.202407133
Published: 16 April 2025
View articletitled, PML mutants from arsenic-resistant patients reveal SUMO1-TOPORS and SUMO2/3-RNF4 degradation pathways
Open the PDF for PML mutants from arsenic-resistant patients reveal SUMO1-TOPORS and SUMO2/3-RNF4 degradation pathways in another window
Includes: Supplementary data
Journal Articles

Regulation of ETAA1-mediated ATR activation couples DNA replication fidelity and genome stability

Divya Achuthankutty, Roshan Singh Thakur, Peter Haahr, Saskia Hoffmann, Alexandros P. Drainas, Anna H. Bizard, Joachim Weischenfeldt, Ian D. Hickson, Niels Mailand
Journal: Journal of Cell Biology
J Cell Biol (2019) 218 (12): 3943–3953.
https://doi.org/10.1083/jcb.201905064
Published: 15 October 2019
View articletitled, Regulation of ETAA1-mediated ATR activation couples DNA replication fidelity and genome stability
Open the PDF for Regulation of ETAA1-mediated ATR activation couples DNA replication fidelity and genome stability in another window
Includes: Supplementary data
Journal Articles

TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress

Saskia Hoffmann, Stine Smedegaard, Kyosuke Nakamura, Gulnahar B. Mortuza, Markus Räschle, Alain Ibañez de Opakua, Yasuyoshi Oka, Yunpeng Feng, Francisco J. Blanco, Matthias Mann, Guillermo Montoya, Anja Groth, Simon Bekker-Jensen, Niels Mailand
Journal: Journal of Cell Biology
J Cell Biol (2015) 212 (1): 63–75.
https://doi.org/10.1083/jcb.201506071
Published: 28 December 2015
View articletitled, TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress
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Includes: Supplementary data
Journal Articles

RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response

Sara L. Poulsen, Rebecca K. Hansen, Sebastian A. Wagner, Loes van Cuijk, Gijsbert J. van Belle, Werner Streicher, Mats Wikström, Chunaram Choudhary, Adriaan B. Houtsmuller, Jurgen A. Marteijn, Simon Bekker-Jensen, Niels Mailand
Journal: Journal of Cell Biology
J Cell Biol (2013) 201 (6): 797–807.
https://doi.org/10.1083/jcb.201212075
Published: 10 June 2013
View articletitled, RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response
Open the PDF for RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response in another window
Includes: Supplementary data
Journal Articles

DNA damage–inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger

Jannie Rendtlew Danielsen, Lou Klitgaard Povlsen, Bine Hare Villumsen, Werner Streicher, Jakob Nilsson, Mats Wikström, Simon Bekker-Jensen, Niels Mailand
Journal: Journal of Cell Biology
J Cell Biol (2012) 197 (2): 179–187.
https://doi.org/10.1083/jcb.201106152
Published: 16 April 2012
View articletitled, DNA damage–inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger
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Includes: Supplementary data
Journal Articles

Human RNF169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaks

Maria Poulsen, Claudia Lukas, Jiri Lukas, Simon Bekker-Jensen, Niels Mailand
Journal: Journal of Cell Biology
J Cell Biol (2012) 197 (2): 189–199.
https://doi.org/10.1083/jcb.201109100
Published: 09 April 2012
View articletitled, Human RNF169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaks
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Includes: Supplementary data
Journal Articles

Nucleotide excision repair–induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response

Jurgen A. Marteijn, Simon Bekker-Jensen, Niels Mailand, Hannes Lans, Petra Schwertman, Audrey M. Gourdin, Nico P. Dantuma, Jiri Lukas, Wim Vermeulen
Journal: Journal of Cell Biology
J Cell Biol (2009) 186 (6): 835–847.
https://doi.org/10.1083/jcb.200902150
Published: 21 September 2009
View articletitled, Nucleotide excision repair–induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response
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Includes: Supplementary data
Journal Articles

Human Fbh1 helicase contributes to genome maintenance via pro- and anti-recombinase activities

Kasper Fugger, Martin Mistrik, Jannie Rendtlew Danielsen, Christoffel Dinant, Jacob Falck, Jiri Bartek, Jiri Lukas, Niels Mailand
Journal: Journal of Cell Biology
J Cell Biol (2009) 186 (5): 655–663.
https://doi.org/10.1083/jcb.200812138
Published: 07 September 2009
View articletitled, Human Fbh1 helicase contributes to genome maintenance via pro- and anti-recombinase activities
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Includes: Supplementary data
Journal Articles

USP7 counteracts SCFβTrCP- but not APCCdh1-mediated proteolysis of Claspin

Helene Faustrup, Simon Bekker-Jensen, Jiri Bartek, Jiri Lukas, Niels Mailand
Journal: Journal of Cell Biology
J Cell Biol (2009) 184 (1): 13–19.
https://doi.org/10.1083/jcb.200807137
Published: 05 January 2009
View articletitled, USP7 counteracts SCFβTrCP- but not APCCdh1-mediated proteolysis of Claspin
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Includes: Supplementary data
Journal Articles

Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage–modified chromatin

Fredrik Melander, Simon Bekker-Jensen, Jacob Falck, Jiri Bartek, Niels Mailand, Jiri Lukas
Journal: Journal of Cell Biology
J Cell Biol (2008) 181 (2): 213–226.
https://doi.org/10.1083/jcb.200708210
Published: 14 April 2008
View articletitled, Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage–modified chromatin
Open the PDF for Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage–modified chromatin in another window
Includes: Supplementary data