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Nicoletta Bobola
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Journal Articles
Journal:
Journal of Cell Biology
Journal of Cell Biology (2017) 216 (9): 2603–2605.
Published: 11 August 2017
Abstract
How transcription factors (TFs) control enhancer and promoter functions to effect changes in gene expression is an important question. In this issue, Hau et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201701154 ) show that the TALE TF MEIS recruits the histone modifier PARP1/ARTD1 at promoters to decompact chromatin and activate transcription.