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John Silke
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Journal Articles

Ndfip1 regulates nuclear Pten import in vivo to promote neuronal survival following cerebral ischemia

Jason Howitt, Jenny Lackovic, Ley-Hian Low, Adam Naguib, Alison Macintyre, Choo-Peng Goh, Jennifer K. Callaway, Vicki Hammond, Tim Thomas, Matthew Dixon, Ulrich Putz, John Silke, Perry Bartlett, Baoli Yang, Sharad Kumar, Lloyd C. Trotman, Seong-Seng Tan
Journal: Journal of Cell Biology
J Cell Biol (2012) 196 (1): 29–36.
https://doi.org/10.1083/jcb.201105009
Published: 02 January 2012
View article titled, Ndfip1 regulates nuclear Pten import in vivo to promote neuronal survival following cerebral ischemia
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Includes: Supplementary data
Journal Articles

Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment

Peter Geserick, Mike Hupe, Maryline Moulin, W. Wei-Lynn Wong, Maria Feoktistova, Beate Kellert, Harald Gollnick, John Silke, Martin Leverkus
Journal: Journal of Cell Biology
J Cell Biol (2009) 187 (7): 1037–1054.
https://doi.org/10.1083/jcb.200904158
Published: 28 December 2009
View article titled, Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment
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Includes: Supplementary data
Journal Articles

TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1–TRAF2 complex to sensitize tumor cells to TNFα

James E. Vince, Diep Chau, Bernard Callus, W. Wei-Lynn Wong, Christine J. Hawkins, Pascal Schneider, Mark McKinlay, Christopher A. Benetatos, Stephen M. Condon, Srinivas K. Chunduru, George Yeoh, Robert Brink, David L. Vaux, John Silke
Journal: Journal of Cell Biology
J Cell Biol (2008) 182 (1): 171–184.
https://doi.org/10.1083/jcb.200801010
Published: 07 July 2008
View article titled, TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1–TRAF2 complex to sensitize tumor cells to TNFα
Open the PDF for TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1–TRAF2 complex to sensitize tumor cells to TNFα in another window
Includes: Supplementary data
Journal Articles

Apaf-1 and caspase-9 accelerate apoptosis, but do not determine whether factor-deprived or drug-treated cells die

Paul G. Ekert, Stuart H. Read, John Silke, Vanessa S. Marsden, Hitto Kaufmann, Christine J. Hawkins, Robert Gerl, Sharad Kumar, David L. Vaux
Journal: Journal of Cell Biology
J Cell Biol (2004) 165 (6): 835–842.
https://doi.org/10.1083/jcb.200312031
Published: 21 June 2004
View article titled, Apaf-1 and caspase-9 accelerate apoptosis, but do not determine whether factor-deprived or drug-treated cells die
Open the PDF for Apaf-1 and caspase-9 accelerate apoptosis, but do not determine whether factor-deprived or drug-treated cells die in another window
Includes: Supplementary data
Journal Articles

The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3– and caspase 9–interacting sites

John Silke, Christine J. Hawkins, Paul G. Ekert, Joanne Chew, Catherine L. Day, Miha Pakusch, Anne M. Verhagen, David L. Vaux
Journal: Journal of Cell Biology
J Cell Biol (2002) 157 (1): 115–124.
https://doi.org/10.1083/jcb.200108085
Published: 01 April 2002
View article titled, The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3– and caspase 9–interacting sites
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Journal Articles

Diablo Promotes Apoptosis by Removing Miha/Xiap from Processed Caspase 9

Paul G. Ekert, John Silke, Christine J. Hawkins, Anne M. Verhagen, David L. Vaux
Journal: Journal of Cell Biology
J Cell Biol (2001) 152 (3): 483–490.
https://doi.org/10.1083/jcb.152.3.483
Published: 29 January 2001
View article titled, Diablo Promotes Apoptosis by Removing Miha/Xiap from Processed Caspase 9
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