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James E. Bear
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Journal Articles

Prolonged depletion of profilin 1 or F-actin causes an adaptive response in microtubules

In Special Collection:
Mechanobiology 2025
Bruno A. Cisterna, Kristen Skruber, Makenzie L. Jane, Caleb I. Camesi, Ivan D. Nguyen, Tatiana M. Liu, Peyton V. Warp, Joseph B. Black, Mitchell T. Butler, James E. Bear, Danielle E. Mor, Tracy-Ann Read, Eric A. Vitriol
Journal: Journal of Cell Biology
J Cell Biol (2024) 223 (7): e202309097.
https://doi.org/10.1083/jcb.202309097
Published: 09 May 2024
View articletitled, Prolonged depletion of profilin 1 or F-actin causes an adaptive response in microtubules
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Includes: Supplementary data
Journal Articles

Local monomer levels and established filaments potentiate non-muscle myosin 2 assembly

In Special Collection:
The Year in Cell Biology: 2024
Melissa A. Quintanilla, Hiral Patel, Huini Wu, Kem A. Sochacki, Shreya Chandrasekar, Matthew Akamatsu, Jeremy D. Rotty, Farida Korobova, James E. Bear, Justin W. Taraska, Patrick W. Oakes, Jordan R. Beach
Journal: Journal of Cell Biology
J Cell Biol (2024) 223 (4): e202305023.
https://doi.org/10.1083/jcb.202305023
Published: 14 February 2024
View articletitled, Local monomer levels and established filaments potentiate non-muscle myosin 2 assembly
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Journal Articles

Coro1B and Coro1C regulate lamellipodia dynamics and cell motility by tuning branched actin turnover

Zayna T. King, Mitchell T. Butler, Max A. Hockenberry, Bhagawat C. Subramanian, Priscila F. Siesser, David M. Graham, Wesley R. Legant, James E. Bear
Journal: Journal of Cell Biology
J Cell Biol (2022) 221 (8): e202111126.
https://doi.org/10.1083/jcb.202111126
Published: 03 June 2022
View articletitled, Coro1B and Coro1C regulate lamellipodia dynamics and cell motility by tuning branched actin turnover
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Includes: Supplementary data
Journal Articles

Enucleated cells reveal differential roles of the nucleus in cell migration, polarity, and mechanotransduction

In Special Collection:
Mechanobiology 2019
David M. Graham, Tomas Andersen, Lisa Sharek, Gunes Uzer, Katheryn Rothenberg, Brenton D. Hoffman, Janet Rubin, Martial Balland, James E. Bear, Keith Burridge
Journal: Journal of Cell Biology
J Cell Biol (2018) 217 (3): 895–914.
https://doi.org/10.1083/jcb.201706097
Published: 19 January 2018
View articletitled, Enucleated cells reveal differential roles of the nucleus in cell migration, polarity, and mechanotransduction
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Includes: Multimedia, Supplementary data
Journal Articles

Self-sorting of nonmuscle myosins IIA and IIB polarizes the cytoskeleton and modulates cell motility

Maria S. Shutova, Sreeja B. Asokan, Shefali Talwar, Richard K. Assoian, James E. Bear, Tatyana M. Svitkina
Journal: Journal of Cell Biology
J Cell Biol (2017) 216 (9): 2877–2889.
https://doi.org/10.1083/jcb.201705167
Published: 12 July 2017
View articletitled, Self-sorting of nonmuscle myosins IIA and IIB polarizes the cytoskeleton and modulates cell motility
Open the PDF for Self-sorting of nonmuscle myosins IIA and IIB polarizes the cytoskeleton and modulates cell motility in another window
Includes: Supplementary data
Journal Articles

GMFβ controls branched actin content and lamellipodial retraction in fibroblasts

Elizabeth M. Haynes, Sreeja B. Asokan, Samantha J. King, Heath E. Johnson, Jason M. Haugh, James E. Bear
Journal: Journal of Cell Biology
J Cell Biol (2015) 209 (6): 803–812.
https://doi.org/10.1083/jcb.201501094
Published: 22 June 2015
View articletitled, GMFβ controls branched actin content and lamellipodial retraction in fibroblasts
Open the PDF for GMFβ controls branched actin content and lamellipodial retraction in fibroblasts in another window
Includes: Supplementary data
Journal Articles

F-actin bundles direct the initiation and orientation of lamellipodia through adhesion-based signaling

Heath E. Johnson, Samantha J. King, Sreeja B. Asokan, Jeremy D. Rotty, James E. Bear, Jason M. Haugh
Journal: Journal of Cell Biology
J Cell Biol (2015) 208 (4): 443–455.
https://doi.org/10.1083/jcb.201406102
Published: 09 February 2015
View articletitled, F-actin bundles direct the initiation and orientation of lamellipodia through adhesion-based signaling
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Includes: Multimedia, Supplementary data
Journal Articles

LKB1 loss in melanoma disrupts directional migration toward extracellular matrix cues

Keefe T. Chan, Sreeja B. Asokan, Samantha J. King, Tao Bo, Evan S. Dubose, Wenjin Liu, Matthew E. Berginski, Jeremy M. Simon, Ian J. Davis, Shawn M. Gomez, Norman E. Sharpless, James E. Bear
Journal: Journal of Cell Biology
J Cell Biol (2014) 207 (2): 299–315.
https://doi.org/10.1083/jcb.201404067
Published: 27 October 2014
View articletitled, LKB1 loss in melanoma disrupts directional migration toward extracellular matrix cues
Open the PDF for LKB1 loss in melanoma disrupts directional migration toward extracellular matrix cues in another window
Includes: Supplementary data
Journal Articles

Loss of Arp2/3 induces an NF-κB–dependent, nonautonomous effect on chemotactic signaling

Congying Wu, Elizabeth M. Haynes, Sreeja B. Asokan, Jeremy M. Simon, Norman E. Sharpless, Albert S. Baldwin, Ian J. Davis, Gary L. Johnson, James E. Bear
Journal: Journal of Cell Biology
J Cell Biol (2013) 203 (6): 907–916.
https://doi.org/10.1083/jcb.201306032
Published: 16 December 2013
View articletitled, Loss of Arp2/3 induces an NF-κB–dependent, nonautonomous effect on chemotactic signaling
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Includes: Supplementary data
Journal Articles

Peering deeply inside the branch

Liang Cai, James E. Bear
Journal: Journal of Cell Biology
J Cell Biol (2008) 180 (5): 853–855.
https://doi.org/10.1083/jcb.200802062
Published: 03 March 2008
View articletitled, Peering deeply inside the branch
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Journal Articles

SCAR, a WASP-related Protein, Isolated as a Suppressor of Receptor Defects in Late Dictyostelium Development

In Special Collection:
JCB65: Cytoskeleton
James E. Bear, John F. Rawls, Charles L. Saxe, III
Journal: Journal of Cell Biology
J Cell Biol (1998) 142 (5): 1325–1335.
https://doi.org/10.1083/jcb.142.5.1325
Published: 07 September 1998
View articletitled, SCAR, a WASP-related Protein, Isolated as a Suppressor of Receptor Defects in Late Dictyostelium Development
Open the PDF for SCAR, a WASP-related Protein, Isolated as a Suppressor of Receptor Defects in Late Dictyostelium Development in another window