Skip to Main Content


Skip Nav Destination


In This Issue

In Focus

Chromatid-untangling enzyme takes longer than expected to complete job.

People & Ideas

Robinson studies the function and evolution of coated vesicle adaptor proteins.



Dlg1 recruits LGN to the cortex of cells in the chick neuroepithelium and may provide instructive cues that drive planar spindle orientation.


Independent of the presence of rDNA repeats, topological constraints imposed by chromosome length and perinuclear attachment determine the efficiency with which sister chromatid intertwines are resolved by topoisomerase II and dynamic microtubules during anaphase.

In spite of global transcriptional inhibition, a decrease in HSF2 expression during mitosis allows for heat shock protein expression and protects cells against proteotoxicity.

By interacting with the collagen cargo receptor component cTAGE5, Sec12 concentrates at ER exit sites and generates the high levels of GTP-bound Sar1 necessary for export of collagen to the Golgi.

Cryo-EM and molecular dynamics simulations reveal unexpected flexibility in individual monomers and a stable interface between monomers in the spiral filaments formed by the ESCRT-III subunit Vps32/CHMP4B.

An interaction with the microtubule-binding protein EB1 enables the desmosomal protein desmoplakin to modify microtubule organization and dynamics near sites of cell–cell contact, subsequently regulating membrane localization of gap junction–forming connexins.

Activation of RhoA-ROCK-BMP signaling reprograms adult human corneal endothelial cells into neural crest–like progenitors, which effectively form corneal endothelial monolayers that may eliminate the need for corneal transplantation.

Close Modal

or Create an Account

Close Modal
Close Modal