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29 June 2009
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On the cover
McConnell et al. reveal a new activity for microvilli in the brush border lining the small intestine. Enzymes including intestinal alkaline phosphatase (green) are sorted into vesicles and released from the tips of microvilli (red) into the gut lumen, where they may help process nutrients and fight intestinal bacteria.
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ISSN 0021-9525
EISSN 1540-8140
In this Issue
In This Issue
In Focus
Microvilli give gut vesicles the brush-off
A surprising new function for intestinal cells in shaping their local environment.
People & Ideas
Antonio Giraldez: At the tip of the microRNA iceberg
Using zebrafish, Giraldez studies how microRNAs guide the body's development.
Feature
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MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes
Michele Bastiani,Libin Liu,Michelle M. Hill,Mark P. Jedrychowski,Susan J. Nixon,Harriet P. Lo,Daniel Abankwa,Robert Luetterforst,Manuel Fernandez-Rojo,Michael R. Breen,Steven P. Gygi,Jorgen Vinten,Piers J. Walser,Kathryn N. North,John F. Hancock,Paul F. Pilch,Robert G. Parton
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