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Volume 183, Issue 7
29 December 2008
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  • Cover Image

    Cover Image

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    On the cover
    DNA single-strand repair protein, Parp-1 (green dots), also helps with doublestrand breaks, according to Sugimura et al. At replicating regions of the genome (red and bue dots) Parp-1 slows the replication fork to allow double-strand repair enzymes to work.
    See page 1203.

  • PDF Icon PDF LinkTable of Contents
  • PDF Icon PDF LinkEditorial Board
ISSN 0021-9525
EISSN 1540-8140
In this Issue

In This Issue

Cardio(lipin) workout beefs up mitochondrial imports
Mitch Leslie
View Articletitled, Cardio(lipin) workout beefs up mitochondrial imports
DNA, just chill
Mitch Leslie
View Articletitled, DNA, just chill
Leptin's long-distance call to the pancreas
Mitch Leslie
View Articletitled, Leptin's long-distance call to the pancreas
Matrix fragments trigger fatal excitement
Mitch Leslie
View Articletitled, Matrix fragments trigger fatal excitement
Slow down, enzymes at work
Mitch Leslie
View Articletitled, Slow down, enzymes at work

People & Ideas

Kai Simons: Membrane master
Caitlin Sedwick
View Articletitled, Kai Simons: Membrane master

Spotlight

EBs clip CLIPs to growing microtubule ends
Torsten Wittmann
View Articletitled, EBs clip CLIPs to growing microtubule ends

Review

Nanotubes, exosomes, and nucleic acid–binding peptides provide novel mechanisms of intercellular communication in eukaryotic cells: implications in health and disease
Mattias Belting,Anders Wittrup
View Articletitled, Nanotubes, exosomes, and nucleic acid–binding peptides provide novel mechanisms of intercellular communication in eukaryotic cells: implications in health and disease

Report

Three-dimensional localization of CENP-A suggests a complex higher order structure of centromeric chromatin
Owen J. Marshall,Alan T. Marshall,K.H. Andy Choo
View Articletitled, Three-dimensional localization of CENP-A suggests a complex higher order structure of centromeric chromatin
PARP-1 ensures regulation of replication fork progression by homologous recombination on damaged DNA
Kazuto Sugimura,Shin-ichiro Takebayashi,Hiroshi Taguchi,Shunichi Takeda,Katsuzumi Okumura
View Articletitled, PARP-1 ensures regulation of replication fork progression by homologous recombination on damaged DNA
The translocator maintenance protein Tam41 is required for mitochondrial cardiolipin biosynthesis
Stephan Kutik,Michael Rissler,Xue Li Guan,Bernard Guiard,Guanghou Shui,Natalia Gebert,Philip N. Heacock,Peter Rehling,William Dowhan,Markus R. Wenk,Nikolaus Pfanner,Nils Wiedemann
View Articletitled, The translocator maintenance protein Tam41 is required for mitochondrial cardiolipin biosynthesis
CLIP-170 tracks growing microtubule ends by dynamically recognizing composite EB1/tubulin-binding sites
Peter Bieling,Stefanie Kandels-Lewis,Ivo A. Telley,Juliette van Dijk,Carsten Janke,Thomas Surrey
View Articletitled, CLIP-170 tracks growing microtubule ends by dynamically recognizing composite EB1/tubulin-binding sites
The sympathetic tone mediates leptin's inhibition of insulin secretion by modulating osteocalcin bioactivity
Eiichi Hinoi,Nan Gao,Dae Young Jung,Vijay Yadav,Tatsuya Yoshizawa,Martin G. Myers, Jr.,Streamson C. Chua, Jr.,Jason K. Kim,Klaus H. Kaestner,Gerard Karsenty
View Articletitled, The sympathetic tone mediates leptin's inhibition of insulin secretion by modulating osteocalcin bioactivity

Article

Coordinated control of self-renewal and differentiation of neural stem cells by Myc and the p19ARF–p53 pathway
Motoshi Nagao,Kenneth Campbell,Kevin Burns,Chia-Yi Kuan,Andreas Trumpp,Masato Nakafuku
View Articletitled, Coordinated control of self-renewal and differentiation of neural stem cells by Myc and the p19<sup>ARF</sup>–p53 pathway
UBF levels determine the number of active ribosomal RNA genes in mammals
Elaine Sanij,Gretchen Poortinga,Kerith Sharkey,Sandy Hung,Timothy P. Holloway,Jaclyn Quin,Elysia Robb,Lee H. Wong,Walter G. Thomas,Victor Stefanovsky,Tom Moss,Lawrence Rothblum,Katherine M. Hannan,Grant A. McArthur,Richard B. Pearson,Ross D. Hannan
View Articletitled, UBF levels determine the number of active ribosomal RNA genes in mammals
The peroxisomal membrane protein import receptor Pex3p is directly transported to peroxisomes by a novel Pex19p- and Pex16p-dependent pathway
Takashi Matsuzaki,Yukio Fujiki
View Articletitled, The peroxisomal membrane protein import receptor Pex3p is directly transported to peroxisomes by a novel Pex19p- and Pex16p-dependent pathway
The microtubule-binding protein CLIP-170 coordinates mDia1 and actin reorganization during CR3-mediated phagocytosis
Elodie Lewkowicz,Floriane Herit,Christophe Le Clainche,Pierre Bourdoncle,Franck Perez,Florence Niedergang
View Articletitled, The microtubule-binding protein CLIP-170 coordinates mDia1 and actin reorganization during CR3-mediated phagocytosis
Proteolytic fragments of laminin promote excitotoxic neurodegeneration by up-regulation of the KA1 subunit of the kainate receptor
Zu-Lin Chen,Huaxu Yu,Wei-Ming Yu,Robert Pawlak,Sidney Strickland
View Articletitled, Proteolytic fragments of laminin promote excitotoxic neurodegeneration by up-regulation of the KA1 subunit of the kainate receptor

Correction

Uniting to save cancer cells
Mitch Leslie
View Articletitled, Uniting to save cancer cells
A false sense of security
Mike Rossner
View Articletitled, A false sense of security

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