Issues

In This Issue

Claudin 11 stops the leaks

Caitlin Sedwick
View Articletitled, Claudin 11 stops the leaks

Parkin cleans house

Caitlin Sedwick
View Articletitled, Parkin cleans house

Dictyostelium cells lay a breadcrumb trail

Caitlin Sedwick
View Articletitled, <em>Dictyostelium</em> cells lay a breadcrumb trail

Cofilin activity is a total coincidence

Caitlin Sedwick
View Articletitled, Cofilin activity is a total coincidence

Dynein gives the “all clear”

Caitlin Sedwick
View Articletitled, Dynein gives the “all clear”

People & Ideas

Brett Lindenbach: Deconstructing and reconstructing hepatitis C

Ruth Williams
View Articletitled, Brett Lindenbach: Deconstructing and reconstructing hepatitis C

Spotlight

Parkin mitochondria in the autophagosome

Heidi M. McBride
View Articletitled, Parkin mitochondria in the autophagosome

Review

The Mad2 partial unfolding model: regulating mitosis through Mad2 conformational switching

John J. Skinner,Stacey Wood,James Shorter,S. Walter Englander,Ben E. Black
View Articletitled, The Mad2 partial unfolding model: regulating mitosis through Mad2 conformational switching

Report

Recruitment of RNA polymerase II cofactor PC4 to DNA damage sites

Oliver Mortusewicz,Wera Roth,Na Li,M. Cristina Cardoso,Michael Meisterernst,Heinrich Leonhardt
View Articletitled, Recruitment of RNA polymerase II cofactor PC4 to DNA damage sites

Multiple autophosphorylation sites are dispensable for murine ATM activation in vivo

Jeremy A. Daniel,Manuela Pellegrini,Ji-Hoon Lee,Tanya T. Paull,Lionel Feigenbaum,André Nussenzweig
View Articletitled, Multiple autophosphorylation sites are dispensable for murine ATM activation in vivo

Schizosaccharomyces pombe Pak-related protein, Pak1p/Orb2p, phosphorylates myosin regulatory light chain to inhibit cytokinesis

Tsui-Han Loo,Mohan Balasubramanian
View Articletitled, <em>Schizosaccharomyces pombe</em> Pak-related protein, Pak1p/Orb2p, phosphorylates myosin regulatory light chain to inhibit cytokinesis

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

In Special Collection: JCB65: Autophagy
Derek Narendra,Atsushi Tanaka,Der-Fen Suen,Richard J. Youle
View Articletitled, Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

Article

Genome-wide analysis reveals a cell cycle–dependent mechanism controlling centromere propagation

Sylvia Erhardt,Barbara G. Mellone,Craig M. Betts,Weiguo Zhang,Gary H. Karpen,Aaron F. Straight
View Articletitled, Genome-wide analysis reveals a cell cycle–dependent mechanism controlling centromere propagation

Phosphorylation regulates targeting of cytoplasmic dynein to kinetochores during mitosis

Jacqueline Whyte,Jason R. Bader,Sinji B.F. Tauhata,Maurice Raycroft,Jessica Hornick,K. Kevin Pfister,William S. Lane,Gordon K. Chan,Edward H. Hinchcliffe,Patricia S. Vaughan,Kevin T. Vaughan
View Articletitled, Phosphorylation regulates targeting of cytoplasmic dynein to kinetochores during mitosis

FAM29A promotes microtubule amplification via recruitment of the NEDD1–γ-tubulin complex to the mitotic spindle

Hui Zhu,Judith A. Coppinger,Chang-Young Jang,John R. Yates, III,Guowei Fang
View Articletitled, FAM29A promotes microtubule amplification via recruitment of the NEDD1–γ-tubulin complex to the mitotic spindle

CaMKII locally encodes L-type channel activity to signal to nuclear CREB in excitation–transcription coupling

Damian G. Wheeler,Curtis F. Barrett,Rachel D. Groth,Parsa Safa,Richard W. Tsien
View Articletitled, CaMKII locally encodes L-type channel activity to signal to nuclear CREB in excitation–transcription coupling

Cofilin is a pH sensor for actin free barbed end formation: role of phosphoinositide binding

Christian Frantz,Gabriela Barreiro,Laura Dominguez,Xiaoming Chen,Robert Eddy,John Condeelis,Mark J.S. Kelly,Matthew P. Jacobson,Diane L. Barber
View Articletitled, Cofilin is a pH sensor for actin free barbed end formation: role of phosphoinositide binding

μ2 adaptin facilitates but is not essential for synaptic vesicle recycling in Caenorhabditis elegans

Mingyu Gu,Kim Schuske,Shigeki Watanabe,Qiang Liu,Paul Baum,Gian Garriga,Erik M. Jorgensen
View Articletitled, μ2 adaptin facilitates but is not essential for synaptic vesicle recycling in <em>Caenorhabditis elegans </em>

Synapses are regulated by the cytoplasmic tyrosine kinase Fer in a pathway mediated by p120catenin, Fer, SHP-2, and β-catenin

Seung-Hye Lee,I.-Feng Peng,Yu Gie Ng,Masahiro Yanagisawa,Shernaz X. Bamji,Lisa P. Elia,Janne Balsamo,Jack Lilien,Panos Z. Anastasiadis,Erik M. Ullian,Louis F. Reichardt
View Articletitled, Synapses are regulated by the cytoplasmic tyrosine kinase Fer in a pathway mediated by p120catenin, Fer, SHP-2, and β-catenin

Tight junctions potentiate the insulative properties of small CNS myelinated axons

Jerome Devaux,Alexander Gow
View Articletitled, Tight junctions potentiate the insulative properties of small CNS myelinated axons

Molecular architecture of inner dynein arms in situ in Chlamydomonas reinhardtii flagella

Khanh Huy Bui,Hitoshi Sakakibara,Tandis Movassagh,Kazuhiro Oiwa,Takashi Ishikawa
View Articletitled, Molecular architecture of inner dynein arms in situ in <em>Chlamydomonas reinhardtii</em> flagella

Regulation of EphB2 activation and cell repulsion by feedback control of the MAPK pathway

Alexei Poliakov,Maria L. Cotrina,Andrea Pasini,David G. Wilkinson
View Articletitled, Regulation of EphB2 activation and cell repulsion by feedback control of the MAPK pathway

Collective cell migration requires vesicular trafficking for chemoattractant delivery at the trailing edge

Paul W. Kriebel,Valarie A. Barr,Erin C. Rericha,Guofeng Zhang,Carole A. Parent
View Articletitled, Collective cell migration requires vesicular trafficking for chemoattractant delivery at the trailing edge