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Issues

Volume 183, Issue 4
17 November 2008
Issue Cover
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  • Cover Image

    Cover Image

    issue cover

    On the cover
    Cells in a model intestine face the right way thanks to Cdc42. The protein ensures the mitotic spindles of gut cells always align perpendicular to the center of the growing structure; in turn this ensures the cell's apical surfaces (green) always face one central lumen.
    See page 625.

  • PDF Icon PDF LinkTable of Contents
  • PDF Icon PDF LinkEditorial Board
ISSN 0021-9525
EISSN 1540-8140
In this Issue

In This Issue

Cdc42 turns the spindle
Mitch Leslie
View Articletitled, Cdc42 turns the spindle
A get-together for caspases
Mitch Leslie
View Articletitled, A get-together for caspases
Axons lose their identity
Mitch Leslie
View Articletitled, Axons lose their identity
Uniting to save cancer cells
Mitch Leslie
View Articletitled, Uniting to save cancer cells
DNA healer
Mitch Leslie
View Articletitled, DNA healer

People & Ideas

Rebecca Heald: Passionate about cycles
Caitlin Sedwick
View Articletitled, Rebecca Heald: Passionate about cycles

Editorial

A false sense of security
Mike Rossner
View Articletitled, A false sense of security

Spotlight

Limiting lumens: a new role for Cdc42
Terry Lechler
View Articletitled, Limiting lumens: a new role for Cdc42
Caspase-8 goes cardiolipin: a new platform to provide mitochondria with microdomains of apoptotic signals?
Luca Scorrano
View Articletitled, Caspase-8 goes cardiolipin: a new platform to provide mitochondria with microdomains of apoptotic signals?

Review

Cytoplasmic diffusion: molecular motors mix it up
Clifford P. Brangwynne,Gijsje H. Koenderink,Frederick C. MacKintosh,David A. Weitz
View Articletitled, Cytoplasmic diffusion: molecular motors mix it up

Report

Nucleolar protein B23/nucleophosmin regulates the vertebrate SUMO pathway through SENP3 and SENP5 proteases
Chawon Yun,Yonggang Wang,Debaditya Mukhopadhyay,Peter Backlund,Nagamalleswari Kolli,Alfred Yergey,Keith D. Wilkinson,Mary Dasso
View Articletitled, Nucleolar protein B23/nucleophosmin regulates the vertebrate SUMO pathway through SENP3 and SENP5 proteases
HP1-β is required for development of the cerebral neocortex and neuromuscular junctions
Rebecca Aucott,Jörn Bullwinkel,Yang Yu,Wei Shi,Mustafa Billur,Jeremy P. Brown,Ursula Menzel,Dimitris Kioussis,Guozheng Wang,Ingrid Reisert,Jörg Weimer,Raj K. Pandita,Girdhar G. Sharma,Tej K. Pandita,Reinald Fundele,Prim B. Singh
View Articletitled, HP1-β is required for development of the cerebral neocortex and neuromuscular junctions
Golgi coiled-coil proteins contain multiple binding sites for Rab family G proteins
Rita Sinka,Alison K. Gillingham,Vangelis Kondylis,Sean Munro
View Articletitled, Golgi coiled-coil proteins contain multiple binding sites for Rab family G proteins
A kinesin-13 mutant catalytically depolymerizes microtubules in ADP
Michael Wagenbach,Sarah Domnitz,Linda Wordeman,Jeremy Cooper
View Articletitled, A kinesin-13 mutant catalytically depolymerizes microtubules in ADP
Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis
Aron B. Jaffe,Noriko Kaji,Joanne Durgan,Alan Hall
View Articletitled, Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis
AnkyrinG is required for maintenance of the axon initial segment and neuronal polarity
Kristian L. Hedstrom,Yasuhiro Ogawa,Matthew N. Rasband
View Articletitled, AnkyrinG is required for maintenance of the axon initial segment and neuronal polarity

Article

Histone H3 lysine 56 acetylation by Rtt109 is crucial for chromosome positioning
Shin-ichiro Hiraga,Sotirios Botsios,Anne D. Donaldson
View Articletitled, Histone H3 lysine 56 acetylation by Rtt109 is crucial for chromosome positioning
Fast regulation of AP-1 activity through interaction of lamin A/C, ERK1/2, and c-Fos at the nuclear envelope
José María González,Ana Navarro-Puche,Berta Casar,Piero Crespo,Vicente Andrés
View Articletitled, Fast regulation of AP-1 activity through interaction of lamin A/C, ERK1/2, and c-Fos at the nuclear envelope
Phosphorylation sites in BubR1 that regulate kinetochore attachment, tension, and mitotic exit
Haomin Huang,James Hittle,Francesca Zappacosta,Roland S. Annan,Avram Hershko,Timothy J. Yen
View Articletitled, Phosphorylation sites in BubR1 that regulate kinetochore attachment, tension, and mitotic exit
Cardiolipin provides an essential activating platform for caspase-8 on mitochondria
In Special Collection: JCB65: Cell Death
Francois Gonzalvez,Zachary T. Schug,Riekelt H. Houtkooper,Elaine D. MacKenzie,David G. Brooks,Ronald J.A. Wanders,Patrice X. Petit,Frédéric M. Vaz,Eyal Gottlieb
View Articletitled, Cardiolipin provides an essential activating platform for caspase-8 on mitochondria
RhoA–ROCK and p38MAPK-MSK1 mediate vitamin D effects on gene expression, phenotype, and Wnt pathway in colon cancer cells
Paloma Ordóñez-Morán,María Jesús Larriba,Héctor G. Pálmer,Ruth A. Valero,Antonio Barbáchano,Mireia Duñach,Antonio García de Herreros,Carlos Villalobos,María Teresa Berciano,Miguel Lafarga,Alberto Muñoz
View Articletitled, RhoA–ROCK and p38MAPK-MSK1 mediate vitamin D effects on gene expression, phenotype, and Wnt pathway in colon cancer cells
Induction of cell retraction by the combined actions of Abl–CrkII and Rho–ROCK1 signaling
XiaoDong Huang,Diana Wu,Hua Jin,Dwayne Stupack,Jean Y.J. Wang
View Articletitled, Induction of cell retraction by the combined actions of Abl–CrkII and Rho–ROCK1 signaling
Differential roles of ArfGAP1, ArfGAP2, and ArfGAP3 in COPI trafficking
Carolin Weimer,Rainer Beck,Priska Eckert,Ingeborg Reckmann,Jörg Moelleken,Britta Brügger,Felix Wieland
View Articletitled, Differential roles of ArfGAP1, ArfGAP2, and ArfGAP3 in COPI trafficking
p120 catenin induces opposing effects on tumor cell growth depending on E-cadherin expression
Edwin Soto,Masahiro Yanagisawa,Laura A. Marlow,John A. Copland,Edith A. Perez,Panos Z. Anastasiadis
View Articletitled, p120 catenin induces opposing effects on tumor cell growth depending on E-cadherin expression

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