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Cellular self-eating promotes pancreatitis

Mitch Leslie
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Alzheimer's protein controls calcium's ins and outs

Mitch Leslie
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How cells make local calls

Mitch Leslie
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Mitochondrial DNA stays home

Mitch Leslie
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Daughter cells share duties

Mitch Leslie
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People & Ideas

Paul Mischel: All about brains

Ruth Williams
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Report

Both daughter cells traffic and exocytose membrane at the cleavage furrow during mammalian cytokinesis

John W. Goss,Derek K. Toomre
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Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells

Rajini Mudhasani,Zhiqing Zhu,Gyorgy Hutvagner,Christine M. Eischen,Stephen Lyle,Lisa L. Hall,Jeanne B. Lawrence,Anthony N. Imbalzano,Stephen N. Jones
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Involvement of autophagy in trypsinogen activation within the pancreatic acinar cells

Daisuke Hashimoto,Masaki Ohmuraya,Masahiko Hirota,Akitsugu Yamamoto,Koichi Suyama,Satoshi Ida,Yuushi Okumura,Etsuhisa Takahashi,Hiroshi Kido,Kimi Araki,Hideo Baba,Noboru Mizushima,Ken-ichi Yamamura
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Cleavage of the signaling mucin Msb2 by the aspartyl protease Yps1 is required for MAPK activation in yeast

Nadia Vadaie,Heather Dionne,Darowan S. Akajagbor,Seth R. Nickerson,Damian J. Krysan,Paul J. Cullen
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Article

Mph1p promotes gross chromosomal rearrangement through partial inhibition of homologous recombination

Soma Banerjee,Stephanie Smith,Ji-Hyun Oum,Hung-Jiun Liaw,Ji-Young Hwang,Nilabja Sikdar,Akira Motegi,Sang Eun Lee,Kyungjae Myung
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Role of Sec61p in the ER-associated degradation of short-lived transmembrane proteins

Daniel C. Scott,Randy Schekman
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SERCA pump activity is physiologically regulated by presenilin and regulates amyloid β production

Kim N. Green,Angelo Demuro,Yama Akbari,Brian D. Hitt,Ian F. Smith,Ian Parker,Frank M. LaFerla
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Mitochondrial nucleoids maintain genetic autonomy but allow for functional complementation

Robert W. Gilkerson,Eric A. Schon,Evelyn Hernandez,Mercy M. Davidson
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Regulation of ROS signal transduction by NADPH oxidase 4 localization

Kai Chen,Michael T. Kirber,Hui Xiao,Yu Yang,John F. Keaney, Jr.
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Chibby cooperates with 14-3-3 to regulate β-catenin subcellular distribution and signaling activity

Feng-Qian Li,Adaobi Mofunanya,Kimberley Harris,Ken-Ichi Takemaru
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Rho-GTPase–dependent filamentous actin dynamics coordinate vesicle targeting and exocytosis during tip growth

Yong Jik Lee,Amy Szumlanski,Erik Nielsen,Zhenbiao Yang
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Glial and neuronal isoforms of Neurofascin have distinct roles in the assembly of nodes of Ranvier in the central nervous system

Barbara Zonta,Steven Tait,Shona Melrose,Heather Anderson,Sheila Harroch,Jennifer Higginson,Diane L. Sherman,Peter J. Brophy
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Nicotinic acetylcholine receptor is internalized via a Rac-dependent, dynamin-independent endocytic pathway

Sudha Kumari,Virginia Borroni,Ashutosh Chaudhry,Baron Chanda,Ramiro Massol,Satyajit Mayor,Francisco J. Barrantes
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ERK5 promotes Src-induced podosome formation by limiting Rho activation

Mark Schramp,Olivia Ying,Tai Young Kim,G. Steven Martin
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Mechanisms and consequences of agonist-induced talin recruitment to platelet integrin αIIbβ3

Naohide Watanabe,Laurent Bodin,Manjula Pandey,Matthias Krause,Shaun Coughlin,Vassiliki A. Boussiotis,Mark H. Ginsberg,Sanford J. Shattil
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