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Issues

Volume 179, Issue 7
31 December 2007
Issue Cover
All Issues
ISSN 0021-9525
EISSN 1540-8140

In This Issue

Acrobatic flexibility of the translocon
Nicole LeBrasseur
View Articletitled, Acrobatic flexibility of the translocon
To bud where no bud has gone before
Nicole LeBrasseur
View Articletitled, To bud where no bud has gone before
Motility without invasion
Nicole LeBrasseur
View Articletitled, Motility without invasion
Translation turns on dendritic cells
Nicole LeBrasseur
View Articletitled, Translation turns on dendritic cells

Research Roundup

Cells within cells (within cells)
Richard Robinson
View Articletitled, Cells within cells (within cells)
The NPC, in detail
Richard Robinson
View Articletitled, The NPC, in detail
tRNA's Los is a gain after damage
Richard Robinson
View Articletitled, tRNA's Los is a gain after damage
Building the immunological bull's eye
Richard Robinson
View Articletitled, Building the immunological bull's eye
Lipid + Alzheimer's plaque = problem
Richard Robinson
View Articletitled, Lipid + Alzheimer's plaque = problem

People & Ideas

Anthony Hyman: From unlikely scientist to Royal Society Fellow
Ruth Williams
View Articletitled, Anthony Hyman: From unlikely scientist to Royal Society Fellow

Spotlight

The expanding role of the ER translocon in membrane protein folding
William R. Skach
View Articletitled, The expanding role of the ER translocon in membrane protein folding

Report

The histone methyltransferase SET8 is required for S-phase progression
Stine Jørgensen,Ingegerd Elvers,Morten Beck Trelle,Tobias Menzel,Morten Eskildsen,Ole Nørregaard Jensen,Thomas Helleday,Kristian Helin,Claus Storgaard Sørensen
View Articletitled, The histone methyltransferase SET8 is required for S-phase progression
Local cortical pulling-force repression switches centrosomal centration and posterior displacement in C. elegans
Akatsuki Kimura,Shuichi Onami
View Articletitled, Local cortical pulling-force repression switches centrosomal centration and posterior displacement in <em>C. elegans </em>
A novel insertion pathway of mitochondrial outer membrane proteins with multiple transmembrane segments
Hidenori Otera,Yohsuke Taira,Chika Horie,Yurina Suzuki,Hiroyuki Suzuki,Kiyoko Setoguchi,Hiroki Kato,Toshihiko Oka,Katsuyoshi Mihara
View Articletitled, A novel insertion pathway of mitochondrial outer membrane proteins with multiple transmembrane segments
Genome-wide analysis demonstrates conserved localization of messenger RNAs to mitotic microtubules
Michael D. Blower,Elma Feric,Karsten Weis,Rebecca Heald
View Articletitled, Genome-wide analysis demonstrates conserved localization of messenger RNAs to mitotic microtubules
Adjacent positioning of cellular structures enabled by a Cdc42 GTPase-activating protein–mediated zone of inhibition
Zongtian Tong,Xiang-Dong Gao,Audrey S. Howell,Indrani Bose,Daniel J. Lew,Erfei Bi
View Articletitled, Adjacent positioning of cellular structures enabled by a Cdc42 GTPase-activating protein–mediated zone of inhibition

Article

DNA-activated protein kinase functions in a newly observed S phase checkpoint that links histone mRNA abundance with DNA replication
Berndt Müller,Jane Blackburn,Carmen Feijoo,Xiujie Zhao,Carl Smythe
View Articletitled, DNA-activated protein kinase functions in a newly observed S phase checkpoint that links histone mRNA abundance with DNA replication
Retinoblastoma tumor suppressor protein–dependent methylation of histone H3 lysine 27 is associated with irreversible cell cycle exit
Alexandre Blais,Chris J.C. van Oevelen,Raphaël Margueron,Diego Acosta-Alvear,Brian David Dynlacht
View Articletitled, Retinoblastoma tumor suppressor protein–dependent methylation of histone H3 lysine 27 is associated with irreversible cell cycle exit
PR-Set7–dependent lysine methylation ensures genome replication and stability through S phase
Mathieu Tardat,Rabih Murr,Zdenko Herceg,Claude Sardet,Eric Julien
View Articletitled, PR-Set7–dependent lysine methylation ensures genome replication and stability through S phase
Regulation of translation is required for dendritic cell function and survival during activation
Hugues Lelouard,Enrico K. Schmidt,Voahirana Camosseto,Giovanna Clavarino,Maurizio Ceppi,Hsiang-Ting Hsu,Philippe Pierre
View Articletitled, Regulation of translation is required for dendritic cell function and survival during activation
Two translocating hydrophilic segments of a nascent chain span the ER membrane during multispanning protein topogenesis
Yuichiro Kida,Fumiko Morimoto,Masao Sakaguchi
View Articletitled, Two translocating hydrophilic segments of a nascent chain span the ER membrane during multispanning protein topogenesis
Apoptosis induction by Bid requires unconventional ubiquitination and degradation of its N-terminal fragment
Stephen W.G. Tait,Evert de Vries,Chiel Maas,Anna M. Keller,Clive S. D'Santos,Jannie Borst
View Articletitled, Apoptosis induction by Bid requires unconventional ubiquitination and degradation of its N-terminal fragment
DIAP2 functions as a mechanism-based regulator of drICE that contributes to the caspase activity threshold in living cells
Paulo S. Ribeiro,Erina Kuranaga,Tencho Tenev,François Leulier,Masayuki Miura,Pascal Meier
View Articletitled, DIAP2 functions as a mechanism-based regulator of drICE that contributes to the caspase activity threshold in living cells
Huntingtin-interacting protein 14, a palmitoyl transferase required for exocytosis and targeting of CSP to synaptic vesicles
Tomoko Ohyama,Patrik Verstreken,Cindy V. Ly,Tanja Rosenmund,Akhila Rajan,An-Chi Tien,Claire Haueter,Karen L. Schulze,Hugo J. Bellen
View Articletitled, Huntingtin-interacting protein 14, a palmitoyl transferase required for exocytosis and targeting of CSP to synaptic vesicles
Molecular basis of synaptic vesicle cargo recognition by the endocytic sorting adaptor stonin 2
Nadja Jung,Martin Wienisch,Mingyu Gu,James B. Rand,Sebastian L. Müller,Gerd Krause,Erik M. Jorgensen,Jürgen Klingauf,Volker Haucke
View Articletitled, Molecular basis of synaptic vesicle cargo recognition by the endocytic sorting adaptor stonin 2
Mechanism of botulinum neurotoxin B and G entry into hippocampal neurons
Min Dong,William H. Tepp,Huisheng Liu,Eric A. Johnson,Edwin R. Chapman
View Articletitled, Mechanism of botulinum neurotoxin B and G entry into hippocampal neurons
Axons of retinal ganglion cells are insulted in the optic nerve early in DBA/2J glaucoma
Gareth R. Howell,Richard T. Libby,Tatjana C. Jakobs,Richard S. Smith,F. Campbell Phalan,Joseph W. Barter,Jessica M. Barbay,Jeffrey K. Marchant,Nagaraju Mahesh,Vittorio Porciatti,Alan V. Whitmore,Richard H. Masland,Simon W. M. John
View Articletitled, Axons of retinal ganglion cells are insulted in the optic nerve early in DBA/2J glaucoma
Type I phosphatidylinositol 4-phosphate 5-kinase controls neutrophil polarity and directional movement
Rosa Ana Lacalle,Rosa M. Peregil,Juan Pablo Albar,Ernesto Merino,Carlos Martínez-A,Isabel Mérida,Santos Mañes
View Articletitled, Type I phosphatidylinositol 4-phosphate 5-kinase controls neutrophil polarity and directional movement
Real-time imaging reveals that noninvasive mammary epithelial acini can contain motile cells
Gray W. Pearson,Tony Hunter
View Articletitled, Real-time imaging reveals that noninvasive mammary epithelial acini can contain motile cells
Sequential roles for myosin-X in BMP6-dependent filopodial extension, migration, and activation of BMP receptors
Xinchun Pi,Rongqin Ren,Russell Kelley,Chunlian Zhang,Martin Moser,Aparna B. Bohil,Melinda DiVito,Richard E. Cheney,Cam Patterson
View Articletitled, Sequential roles for myosin-X in BMP6-dependent filopodial extension, migration, and activation of BMP receptors
Zasp is required for the assembly of functional integrin adhesion sites
Klodiana Jani,Frieder Schöck
View Articletitled, Zasp is required for the assembly of functional integrin adhesion sites
Mice deficient in involucrin, envoplakin, and periplakin have a defective epidermal barrier
Lisa M. Sevilla,Rachida Nachat,Karen R. Groot,John F. Klement,Jouni Uitto,Philippe Djian,Arto Määttä,Fiona M. Watt
View Articletitled, Mice deficient in involucrin, envoplakin, and periplakin have a defective epidermal barrier

Correction

Alternative function for the mitochondrial SAM complex in biogenesis of α-helical TOM proteins
Diana Stojanovski,Bernard Guiard,Vera Kozjak-Pavlovic,Nikolaus Pfanner,Chris Meisinger
View Articletitled, Alternative function for the mitochondrial SAM complex in biogenesis of α-helical TOM proteins

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