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Volume 173, Issue 2
24 April 2006
Journal of Cell Biology Cover Image for Volume 173, Issue 2
All Issues
ISSN 0021-9525
EISSN 1540-8140

In This Issue

Spill and kill
Nicole LeBrasseur
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Repair road map
Nicole LeBrasseur
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Flux without sliding
Nicole LeBrasseur
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To each nucleus its own ER
Nicole LeBrasseur
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Research Roundup

The physics of chaperones
William A. Wells
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Immune to weight loss
William A. Wells
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Outdoor decision-making
William A. Wells
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Mixed-up DNA
William A. Wells
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Stressful betrayal
William A. Wells
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From the Archive

Dying on cue
Mitch Leslie
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Hold on for dear life
Mitch Leslie
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An unattached kinetochore screams “Wait!”
Kendall Powell
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Integrin signal transduction
Mitch Leslie
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Review

Structural activation of Mad2 in the mitotic spindle checkpoint: the two-state Mad2 model versus the Mad2 template model
Hongtao Yu
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CAR-1 and Trailer hitch: driving mRNP granule function at the ER?
Carolyn J. Decker,Roy Parker
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Caspases leave the beaten track: caspase-mediated activation of NF-κB
Mohamed Lamkanfi,Wim Declercq,Tom Vanden Berghe,Peter Vandenabeele
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Report

Kinesin 5–independent poleward flux of kinetochore microtubules in PtK1 cells
Lisa A. Cameron,Ge Yang,Daniela Cimini,Julie C. Canman,Olga Kisurina-Evgenieva,Alexey Khodjakov,Gaudenz Danuser,E.D. Salmon
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Direct requirement for Xmus101 in ATR-mediated phosphorylation of Claspin bound Chk1 during checkpoint signaling
Shan Yan,Howard D. Lindsay,W. Matthew Michael
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Direct in vivo monitoring of sarcoplasmic reticulum Ca2+ and cytosolic cAMP dynamics in mouse skeletal muscle
Rüdiger Rudolf,Paulo J. Magalhães,Tullio Pozzan
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Article

Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks
In Special Collection: JCB65: DNA Replication and Repair
Simon Bekker-Jensen,Claudia Lukas,Risa Kitagawa,Fredrik Melander,Michael B. Kastan,Jiri Bartek,Jiri Lukas
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Stepwise RNP assembly at the site of H/ACA RNA transcription in human cells
Xavier Darzacq,Nupur Kittur,Sujayita Roy,Yaron Shav-Tal,Robert H. Singer,U. Thomas Meier
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The secretory membrane system in the Drosophila syncytial blastoderm embryo exists as functionally compartmentalized units around individual nuclei
David Frescas,Manos Mavrakis,Holger Lorenz,Robert DeLotto,Jennifer Lippincott-Schwartz
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Lysosomal biogenesis and function is critical for necrotic cell death in Caenorhabditis elegans
Marta Artal-Sanz,Chrysanthi Samara,Popi Syntichaki,Nektarios Tavernarakis
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Synaptotagmin IV is necessary for the maturation of secretory granules in PC12 cells
Malika Ahras,Grant P. Otto,Sharon A. Tooze
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Ovol1 regulates the growth arrest of embryonic epidermal progenitor cells and represses c-myc transcription
Mahalakshmi Nair,Andy Teng,Virginia Bilanchone,Anshu Agrawal,Baoan Li,Xing Dai
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JNK1 phosphorylation of SCG10 determines microtubule dynamics and axodendritic length
Tatsiana Tararuk,Nina Östman,Wenrui Li,Benny Björkblom,Artur Padzik,Justyna Zdrojewska,Vesa Hongisto,Thomas Herdegen,Witold Konopka,Michael J. Courtney,Eleanor T. Coffey
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Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning
Sheng-Li Cai,Andrew R. Tee,John D. Short,Judith M. Bergeron,Jinhee Kim,Jianjun Shen,Ruifeng Guo,Charles L. Johnson,Kaoru Kiguchi,Cheryl Lyn Walker
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A kinase-deficient TrkC receptor isoform activates Arf6–Rac1 signaling through the scaffold protein tamalin
Pedro F. Esteban,Hye-Young Yoon,Jodi Becker,Susan G. Dorsey,Paola Caprari,Mary Ellen Palko,Vincenzo Coppola,H. Uri Saragovi,Paul A. Randazzo,Lino Tessarollo
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Estrogen transactivates EGFR via the sphingosine 1-phosphate receptor Edg-3: the role of sphingosine kinase-1
Olga Sukocheva,Carol Wadham,Andrew Holmes,Nathaniel Albanese,Emily Verrier,Feng Feng,Alex Bernal,Claudia K. Derian,Axel Ullrich,Mathew A. Vadas,Pu Xia
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Of Interest in J. Exp. Med.
Dystroglycan is selectively cleaved at the parenchymal basement membrane at sites of leukocyte extravasation in experimental autoimmune encephalomyelitis
Smriti Agrawal,Per Anderson,Madeleine Durbeej,Nico van Rooijen,Fredrik Ivars,Ghislain Opdenakker,Lydia M. Sorokin
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Of Interest in J. Exp. Med.
Postnatal acquisition of endotoxin tolerance in intestinal epithelial cells
Michael Lotz,Dominique Gütle,Sabrina Walther,Sandrine Ménard,Christian Bogdan,Mathias W. Hornef
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Of Interest in J. Exp. Med.
Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection
Ari B. Molofsky,Brenda G. Byrne,Natalie N. Whitfield,Cressida A. Madigan,Etsu T. Fuse,Kazuhiro Tateda,Michele S. Swanson
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Correction

Correction: A “traffic control” role for TGFβ3: orchestrating dermal and epidermal cell motility during wound healing
Balaji Bandyopadhyay,Jianhua Fan,Shengxi Guan,Yong Li,Mei Chen,David T. Woodley,Wei Li
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