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Volume 150, Issue 1
10 July 2000
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    Cover Image

    issue cover
    Cover picture: Gallery of electron micrographs of Drosophila 26S proteasomes with gold-labeled ubiquitin-aldehyde, a potent inhibitor of an intrinsic deubiquitylating activity. The averaged images map the corresponding subunit of the regulatory complex to the interface between the base and lid subcomplexes. See related article in this issue by Hölzl et al., 119-129.
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ISSN 0021-9525
EISSN 1540-8140
In this Issue

Article

CENP-meta, an Essential Kinetochore Kinesin Required for the Maintenance of Metaphase Chromosome Alignment in Drosophila
Jennifer K. Yucel,Janet D. Marszalek,J. Richard McIntosh,Lawrence S.B. Goldstein,Don W. Cleveland,Alastair Valentine Philp
View Articletitled, <em>CENP-meta,</em> an Essential Kinetochore Kinesin Required for the Maintenance of Metaphase Chromosome Alignment in <em>Drosophila</em>
Mitotic Transcription Repression in Vivo in the Absence of Nucleosomal Chromatin Condensation
Charlotte A. Spencer,Michael J. Kruhlak,Heather L. Jenkins,Xuejun Sun,David P. Bazett-Jones
View Articletitled, Mitotic Transcription Repression in Vivo in the Absence of Nucleosomal Chromatin Condensation
Transcription Factor Erg Variants and Functional Diversification of Chondrocytes during Limb Long Bone Development
Masahiro Iwamoto,Yoshinobu Higuchi,Eiki Koyama,Motomi Enomoto-Iwamoto,Kojiro Kurisu,Helena Yeh,William R. Abrams,Joel Rosenbloom,Maurizio Pacifici
View Articletitled, Transcription Factor Erg Variants and Functional Diversification of Chondrocytes during Limb Long Bone Development
Reduced Mobility of the Alternate Splicing Factor (Asf) through the Nucleoplasm and Steady State Speckle Compartments
Michael J. Kruhlak,Melody A. Lever,Wolfgang Fischle,Eric Verdin,David P. Bazett-Jones,Michael J. Hendzel
View Articletitled, Reduced Mobility of the Alternate Splicing Factor (Asf) through the Nucleoplasm and Steady State Speckle Compartments
Role of the Cytoplasmic Segments of Sec61α in the Ribosome-Binding and Translocation-Promoting Activities of the Sec61 Complex
David Raden,Weiqun Song,Reid Gilmore
View Articletitled, Role of the Cytoplasmic Segments of Sec61α in the Ribosome-Binding and Translocation-Promoting Activities of the Sec61 Complex
The Heat Shock Protein Ssa2p Is Required for Import of Fructose-1,6-Bisphosphatase into Vid Vesicles
C. Randell Brown,Jameson A. McCann,Hui-Ling Chiang
View Articletitled, The Heat Shock Protein Ssa2p Is Required for Import of Fructose-1,6-Bisphosphatase into Vid Vesicles
The Unfolded Protein Response Regulates Multiple Aspects of Secretory and Membrane Protein Biogenesis and Endoplasmic Reticulum Quality Control
Davis T.W. Ng,Eric D. Spear,Peter Walter
View Articletitled, The Unfolded Protein Response Regulates Multiple Aspects of Secretory and Membrane Protein Biogenesis and Endoplasmic Reticulum Quality Control
Molecular Basis for Rab Prenylation
Christelle Alory,William E. Balch
View Articletitled, Molecular Basis for Rab Prenylation
Close Is Not Enough: Snare-Dependent Membrane Fusion Requires an Active Mechanism That Transduces Force to Membrane Anchors
James A. McNew,Thomas Weber,Francesco Parlati,Robert J. Johnston,Thomas J. Melia,Thomas H. Söllner,James E. Rothman
View Articletitled, Close Is Not Enough<span class="subtitle-colon">: </span><span class="subtitle">Snare-Dependent Membrane Fusion Requires an Active Mechanism That Transduces Force to Membrane Anchors</span>
The Regulatory Complex of Drosophila melanogaster 26s Proteasomes: Subunit Composition and Localization of a Deubiquitylating Enzyme
Harald Hölzl,Barbara Kapelari,Josef Kellermann,Erika Seemüller,Máté Sümegi,Andor Udvardy,Ohad Medalia,Joseph Sperling,Shirley A. Müller,Andreas Engel,Wolfgang Baumeister
View Articletitled, The Regulatory Complex of <em>Drosophila melanogaster</em> 26s Proteasomes<span class="subtitle-colon">: </span><span class="subtitle">Subunit Composition and Localization of a Deubiquitylating Enzyme</span>
Caspase Inhibition Extends the Commitment to Neuronal Death Beyond Cytochrome c Release to the Point of Mitochondrial Depolarization
Mohanish Deshmukh,Keisuke Kuida,Eugene M. Johnson, Jr.
View Articletitled, Caspase Inhibition Extends the Commitment to Neuronal Death Beyond Cytochrome <em>c</em> Release to the Point of Mitochondrial Depolarization
Evidence That Dynamin-2 Functions as a Signal-Transducing Gtpase
Kenneth N. Fish,Sandra L. Schmid,Hanna Damke
View Articletitled, Evidence That Dynamin-2 Functions as a Signal-Transducing Gtpase
Sphingomyelin Hydrolysis to Ceramide during the Execution Phase of Apoptosis Results from Phospholipid Scrambling and Alters Cell-Surface Morphology
Annemiek D. Tepper,Paula Ruurs,Therese Wiedmer,Peter J. Sims,Jannie Borst,Wim J. van Blitterswijk
View Articletitled, Sphingomyelin Hydrolysis to Ceramide during the Execution Phase of Apoptosis Results from Phospholipid Scrambling and Alters Cell-Surface Morphology
Glutamate Slows Axonal Transport of Neurofilaments in Transfected Neurons
Steven Ackerley,Andrew J. Grierson,Janet Brownlees,Paul Thornhill,Brian H. Anderton,P. Nigel Leigh,Christopher E. Shaw,Christopher C.J. Miller
View Articletitled, Glutamate Slows Axonal Transport of Neurofilaments in Transfected Neurons
Ankyrin–Tiam1 Interaction Promotes Rac1 Signaling and Metastatic Breast Tumor Cell Invasion and Migration
Lilly Y.W. Bourguignon,Hongbo Zhu,Lijun Shao,Yue Wei Chen
View Articletitled, Ankyrin–Tiam1 Interaction Promotes Rac1 Signaling and Metastatic Breast Tumor Cell Invasion and Migration
Morphogenic Effects of Ezrin Require a Phosphorylation-Induced Transition from Oligomers to Monomers at the Plasma Membrane
Alexis Gautreau,Daniel Louvard,Monique Arpin
View Articletitled, Morphogenic Effects of Ezrin Require a Phosphorylation-Induced Transition from Oligomers to Monomers at the Plasma Membrane
Agrin-Induced Acetylcholine Receptor Clustering Is Mediated by the Small Guanosine Triphosphatases Rac and Cdc42
Christi Weston,Barry Yee,Eldad Hod,Joav Prives
View Articletitled, Agrin-Induced Acetylcholine Receptor Clustering Is Mediated by the Small Guanosine Triphosphatases Rac and Cdc42
Intracellular Ph Regulation by Na+/H+ Exchange Requires Phosphatidylinositol 4,5-Bisphosphate
Orit Aharonovitz,Hans C. Zaun,Tamas Balla,John D. York,John Orlowski,Sergio Grinstein
View Articletitled, Intracellular Ph Regulation by Na<sup>+</sup>/H<sup>+</sup> Exchange Requires Phosphatidylinositol 4,5-Bisphosphate
WNT/Frizzled-2 Signaling Induces Aggregation and Adhesion among Cardiac Myocytes by Increased Cadherin–β-Catenin Complex
Toshihiko Toyofuku,Zhang Hong,Tsunehiko Kuzuya,Michihiko Tada,Masatsugu Hori
View Articletitled, WNT/Frizzled-2 Signaling Induces Aggregation and Adhesion among Cardiac Myocytes by Increased Cadherin–β-Catenin Complex
Intercellular Adhesion Molecule-5 Induces Dendritic Outgrowth by Homophilic Adhesion
Li Tian,Henrietta Nyman,Patrick Kilgannon,Yoshihiro Yoshihara,Kensaku Mori,Leif C. Andersson,Sami Kaukinen,Heikki Rauvala,W. Michael Gallatin,Carl G. Gahmberg
View Articletitled, Intercellular Adhesion Molecule-5 Induces Dendritic Outgrowth by Homophilic Adhesion
The UNC-112 Gene in Caenorhabditis elegansEncodes a Novel Component of Cell–Matrix Adhesion Structures Required for Integrin Localization in the Muscle Cell Membrane
Teresa M. Rogalski,Gregory P. Mullen,Mary M. Gilbert,Benjamin D. Williams,Donald G. Moerman
View Articletitled, The <em><span class="small-caps">UNC-112</span></em> Gene in <em>Caenorhabditis elegans</em>Encodes a Novel Component of Cell–Matrix Adhesion Structures Required for Integrin Localization in the Muscle Cell Membrane

In This Issue

In This Issue
View Articletitled, In This Issue

Report

Creb-Binding Protein (Cbp/P300) and RNA Polymerase II Colocalize in Transcriptionally Active Domains in the Nucleus
Anna von Mikecz,Suisheng Zhang,Marc Montminy,Eng M. Tan,Peter Hemmerich
View Articletitled, Creb-Binding Protein (Cbp/P300) and RNA Polymerase II Colocalize in Transcriptionally Active Domains in the Nucleus
Fibroblast Growth Factor 2 Internal Ribosome Entry Site (Ires) Activity Ex Vivo and in Transgenic Mice Reveals a Stringent Tissue-Specific Regulation
Laurent Créancier,Dominique Morello,Pascale Mercier,Anne-Catherine Prats
View Articletitled, Fibroblast Growth Factor 2 Internal Ribosome Entry Site (Ires) Activity Ex Vivo and in Transgenic Mice Reveals a Stringent Tissue-Specific Regulation

Review

Seeking Common Ground in Nuclear Complexity
Lindsay S. Shopland,Jeanne B. Lawrence
View Articletitled, Seeking Common Ground in Nuclear Complexity
Aaa Proteins: Lords of the Ring
Ronald D. Vale
View Articletitled, Aaa Proteins<span class="subtitle-colon">: </span><span class="subtitle">Lords of the Ring</span>
Apoptosis and Sphingomyelin Hydrolysis: The Flip Side
Douglas R. Green
View Articletitled, Apoptosis and Sphingomyelin Hydrolysis<span class="subtitle-colon">: </span><span class="subtitle">The Flip Side</span>
Unc112: A New Regulator of Cell–Extracellular Matrix Adhesions?
Michael D. Schaller
View Articletitled, Unc112<span class="subtitle-colon">: </span><span class="subtitle">A New Regulator of Cell–Extracellular Matrix Adhesions?</span>

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