Issues

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CENP-meta, an Essential Kinetochore Kinesin Required for the Maintenance of Metaphase Chromosome Alignment in Drosophila

Jennifer K. Yucel,Janet D. Marszalek,J. Richard McIntosh,Lawrence S.B. Goldstein,Don W. Cleveland,Alastair Valentine Philp
View Articletitled, <em>CENP-meta,</em> an Essential Kinetochore Kinesin Required for the Maintenance of Metaphase Chromosome Alignment in <em>Drosophila</em>

Mitotic Transcription Repression in Vivo in the Absence of Nucleosomal Chromatin Condensation

Charlotte A. Spencer,Michael J. Kruhlak,Heather L. Jenkins,Xuejun Sun,David P. Bazett-Jones
View Articletitled, Mitotic Transcription Repression in Vivo in the Absence of Nucleosomal Chromatin Condensation

Transcription Factor Erg Variants and Functional Diversification of Chondrocytes during Limb Long Bone Development

Masahiro Iwamoto,Yoshinobu Higuchi,Eiki Koyama,Motomi Enomoto-Iwamoto,Kojiro Kurisu,Helena Yeh,William R. Abrams,Joel Rosenbloom,Maurizio Pacifici
View Articletitled, Transcription Factor Erg Variants and Functional Diversification of Chondrocytes during Limb Long Bone Development

Reduced Mobility of the Alternate Splicing Factor (Asf) through the Nucleoplasm and Steady State Speckle Compartments

Michael J. Kruhlak,Melody A. Lever,Wolfgang Fischle,Eric Verdin,David P. Bazett-Jones,Michael J. Hendzel
View Articletitled, Reduced Mobility of the Alternate Splicing Factor (Asf) through the Nucleoplasm and Steady State Speckle Compartments

Role of the Cytoplasmic Segments of Sec61α in the Ribosome-Binding and Translocation-Promoting Activities of the Sec61 Complex

David Raden,Weiqun Song,Reid Gilmore
View Articletitled, Role of the Cytoplasmic Segments of Sec61α in the Ribosome-Binding and Translocation-Promoting Activities of the Sec61 Complex

The Heat Shock Protein Ssa2p Is Required for Import of Fructose-1,6-Bisphosphatase into Vid Vesicles

C. Randell Brown,Jameson A. McCann,Hui-Ling Chiang
View Articletitled, The Heat Shock Protein Ssa2p Is Required for Import of Fructose-1,6-Bisphosphatase into Vid Vesicles

The Unfolded Protein Response Regulates Multiple Aspects of Secretory and Membrane Protein Biogenesis and Endoplasmic Reticulum Quality Control

Davis T.W. Ng,Eric D. Spear,Peter Walter
View Articletitled, The Unfolded Protein Response Regulates Multiple Aspects of Secretory and Membrane Protein Biogenesis and Endoplasmic Reticulum Quality Control

Molecular Basis for Rab Prenylation

Christelle Alory,William E. Balch
View Articletitled, Molecular Basis for Rab Prenylation

Close Is Not Enough: Snare-Dependent Membrane Fusion Requires an Active Mechanism That Transduces Force to Membrane Anchors

James A. McNew,Thomas Weber,Francesco Parlati,Robert J. Johnston,Thomas J. Melia,Thomas H. Söllner,James E. Rothman
View Articletitled, Close Is Not Enough<span class="subtitle-colon">: </span><span class="subtitle">Snare-Dependent Membrane Fusion Requires an Active Mechanism That Transduces Force to Membrane Anchors</span>

The Regulatory Complex of Drosophila melanogaster 26s Proteasomes: Subunit Composition and Localization of a Deubiquitylating Enzyme

Harald Hölzl,Barbara Kapelari,Josef Kellermann,Erika Seemüller,Máté Sümegi,Andor Udvardy,Ohad Medalia,Joseph Sperling,Shirley A. Müller,Andreas Engel,Wolfgang Baumeister
View Articletitled, The Regulatory Complex of <em>Drosophila melanogaster</em> 26s Proteasomes<span class="subtitle-colon">: </span><span class="subtitle">Subunit Composition and Localization of a Deubiquitylating Enzyme</span>

Caspase Inhibition Extends the Commitment to Neuronal Death Beyond Cytochrome c Release to the Point of Mitochondrial Depolarization

Mohanish Deshmukh,Keisuke Kuida,Eugene M. Johnson, Jr.
View Articletitled, Caspase Inhibition Extends the Commitment to Neuronal Death Beyond Cytochrome <em>c</em> Release to the Point of Mitochondrial Depolarization

Evidence That Dynamin-2 Functions as a Signal-Transducing Gtpase

Kenneth N. Fish,Sandra L. Schmid,Hanna Damke
View Articletitled, Evidence That Dynamin-2 Functions as a Signal-Transducing Gtpase

Sphingomyelin Hydrolysis to Ceramide during the Execution Phase of Apoptosis Results from Phospholipid Scrambling and Alters Cell-Surface Morphology

Annemiek D. Tepper,Paula Ruurs,Therese Wiedmer,Peter J. Sims,Jannie Borst,Wim J. van Blitterswijk
View Articletitled, Sphingomyelin Hydrolysis to Ceramide during the Execution Phase of Apoptosis Results from Phospholipid Scrambling and Alters Cell-Surface Morphology

Glutamate Slows Axonal Transport of Neurofilaments in Transfected Neurons

Steven Ackerley,Andrew J. Grierson,Janet Brownlees,Paul Thornhill,Brian H. Anderton,P. Nigel Leigh,Christopher E. Shaw,Christopher C.J. Miller
View Articletitled, Glutamate Slows Axonal Transport of Neurofilaments in Transfected Neurons

Ankyrin–Tiam1 Interaction Promotes Rac1 Signaling and Metastatic Breast Tumor Cell Invasion and Migration

Lilly Y.W. Bourguignon,Hongbo Zhu,Lijun Shao,Yue Wei Chen
View Articletitled, Ankyrin–Tiam1 Interaction Promotes Rac1 Signaling and Metastatic Breast Tumor Cell Invasion and Migration

Morphogenic Effects of Ezrin Require a Phosphorylation-Induced Transition from Oligomers to Monomers at the Plasma Membrane

Alexis Gautreau,Daniel Louvard,Monique Arpin
View Articletitled, Morphogenic Effects of Ezrin Require a Phosphorylation-Induced Transition from Oligomers to Monomers at the Plasma Membrane

Agrin-Induced Acetylcholine Receptor Clustering Is Mediated by the Small Guanosine Triphosphatases Rac and Cdc42

Christi Weston,Barry Yee,Eldad Hod,Joav Prives
View Articletitled, Agrin-Induced Acetylcholine Receptor Clustering Is Mediated by the Small Guanosine Triphosphatases Rac and Cdc42

Intracellular Ph Regulation by Na+/H+ Exchange Requires Phosphatidylinositol 4,5-Bisphosphate

Orit Aharonovitz,Hans C. Zaun,Tamas Balla,John D. York,John Orlowski,Sergio Grinstein
View Articletitled, Intracellular Ph Regulation by Na<sup>+</sup>/H<sup>+</sup> Exchange Requires Phosphatidylinositol 4,5-Bisphosphate

WNT/Frizzled-2 Signaling Induces Aggregation and Adhesion among Cardiac Myocytes by Increased Cadherin–β-Catenin Complex

Toshihiko Toyofuku,Zhang Hong,Tsunehiko Kuzuya,Michihiko Tada,Masatsugu Hori
View Articletitled, WNT/Frizzled-2 Signaling Induces Aggregation and Adhesion among Cardiac Myocytes by Increased Cadherin–β-Catenin Complex

Intercellular Adhesion Molecule-5 Induces Dendritic Outgrowth by Homophilic Adhesion

Li Tian,Henrietta Nyman,Patrick Kilgannon,Yoshihiro Yoshihara,Kensaku Mori,Leif C. Andersson,Sami Kaukinen,Heikki Rauvala,W. Michael Gallatin,Carl G. Gahmberg
View Articletitled, Intercellular Adhesion Molecule-5 Induces Dendritic Outgrowth by Homophilic Adhesion

The UNC-112 Gene in Caenorhabditis elegansEncodes a Novel Component of Cell–Matrix Adhesion Structures Required for Integrin Localization in the Muscle Cell Membrane

Teresa M. Rogalski,Gregory P. Mullen,Mary M. Gilbert,Benjamin D. Williams,Donald G. Moerman
View Articletitled, The <em><span class="small-caps">UNC-112</span></em> Gene in <em>Caenorhabditis elegans</em>Encodes a Novel Component of Cell–Matrix Adhesion Structures Required for Integrin Localization in the Muscle Cell Membrane

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Report

Creb-Binding Protein (Cbp/P300) and RNA Polymerase II Colocalize in Transcriptionally Active Domains in the Nucleus

Anna von Mikecz,Suisheng Zhang,Marc Montminy,Eng M. Tan,Peter Hemmerich
View Articletitled, Creb-Binding Protein (Cbp/P300) and RNA Polymerase II Colocalize in Transcriptionally Active Domains in the Nucleus

Fibroblast Growth Factor 2 Internal Ribosome Entry Site (Ires) Activity Ex Vivo and in Transgenic Mice Reveals a Stringent Tissue-Specific Regulation

Laurent Créancier,Dominique Morello,Pascale Mercier,Anne-Catherine Prats
View Articletitled, Fibroblast Growth Factor 2 Internal Ribosome Entry Site (Ires) Activity Ex Vivo and in Transgenic Mice Reveals a Stringent Tissue-Specific Regulation

Review

Seeking Common Ground in Nuclear Complexity

Lindsay S. Shopland,Jeanne B. Lawrence
View Articletitled, Seeking Common Ground in Nuclear Complexity

Aaa Proteins: Lords of the Ring

Ronald D. Vale
View Articletitled, Aaa Proteins<span class="subtitle-colon">: </span><span class="subtitle">Lords of the Ring</span>

Apoptosis and Sphingomyelin Hydrolysis: The Flip Side

Douglas R. Green
View Articletitled, Apoptosis and Sphingomyelin Hydrolysis<span class="subtitle-colon">: </span><span class="subtitle">The Flip Side</span>

Unc112: A New Regulator of Cell–Extracellular Matrix Adhesions?

Michael D. Schaller
View Articletitled, Unc112<span class="subtitle-colon">: </span><span class="subtitle">A New Regulator of Cell–Extracellular Matrix Adhesions?</span>