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Reviews on Stem Cells 2018

We are pleased to present this collection of reviews on stem cells, the topic of the 2018 ASCB Doorstep Meeting. Learn about stem cells during development beginning with the changes in DNA methylation, chromatin accessibility, and topological architecture that occur during the reprogramming to totipotency in the early embryo, as well as the epigenetic and epitranscriptomic mechanisms that regulate the lineage specification of neural progenitor cells in the developing brain. Read about the mechanisms of asymmetric stem cell division that balance stem cell self-renewal and differentiation. Finally, learn about how a decline in stem cell renewal and function with aging affects tissue homeostasis and regeneration.

Image: iStock.com/emarys

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Review
Sabrina Ladstätter; Kikuë Tachibana
DOI: 10.1083/jcb.201807044
Review
Zsolt G. Venkei; Yukiko M. Yamashita
DOI: 10.1083/jcb.201807037
Review
Ki-Jun Yoon; Caroline Vissers; Guo-li Ming; Hongjun Song
DOI: 10.1083/jcb.201802117
Review
Brice E. Keyes; Elaine Fuchs
DOI: 10.1083/jcb.201708099
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