The in vitro assembly of myosin purified from calf aorta muscle has been studied by electron microscopy. Two types of filament are formed: short bipolar filament similar to those formed from skeletal muscle myosin, and longer "side-polar" filaments having cross bridges with a single polarity along the entire length of one side and the opposite polarity along the other side. Unlike the case with skeletal myosin filaments, antiparallel interactions between myosin molecules occur along the whole length of side-polar filaments. The side-polar structure may be related to the in vivo form of myosin in vertebrate smooth muscle.
Article| December 01 1977
Assembly of smooth muscle myosin into side-polar filaments.
Online Issn: 1540-8140
Print Issn: 0021-9525
J Cell Biol (1977) 75 (3): 990–996.
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R Craig, J Megerman; Assembly of smooth muscle myosin into side-polar filaments.. J Cell Biol 1 December 1977; 75 (3): 990–996. doi: https://doi.org/10.1083/jcb.75.3.990
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