After removal of one mouse kidney, compensatory hypertrophy in the remaining kidney is marked in 2 days by a 20% average increase in ribosomal RNA (rRNA) per cell. Both 28S and 18S RNA are conserved during the initial stages of compensatory renal hypertrophy to an extent sufficient to account for the rest of the observed accumulation of rRNA. Like some cultured cells, the kidney conserves rRNA during physiological growth.
Article| June 01 1976
Conservation of ribosomal RNA during compensatory renal hypertrophy. A major mechanism in RNA accretion.
W T Melvin
R A Malt
Online ISSN: 1540-8140
Print ISSN: 0021-9525
J Cell Biol (1976) 69 (3): 548–556.
W T Melvin, A Kumar, R A Malt; Conservation of ribosomal RNA during compensatory renal hypertrophy. A major mechanism in RNA accretion.. J Cell Biol 1 June 1976; 69 (3): 548–556. doi: https://doi.org/10.1083/jcb.69.3.548
Download citation file: