Glycine, an inhibitory transmitter in spinal cord, is taken up into specific nerve terminals by means of a unique high-affinity uptake system. In this study, [3H]glycine was directly microinjected into rat ventral horn in vivo and electron microscope autoradiography used to localize the label in various anatomic compartments. Quantiative analysis showed that [3H]glycine labeled a high proportion of axosomatic and axodendritic synapses which presumably act to inhibit spinal motor neurons.
Glycine-specific synapses in rat spinal cord. Identification by electron microscope autoradiography.
D L Price, A Stocks, J W Griffin, A Young, K Peck; Glycine-specific synapses in rat spinal cord. Identification by electron microscope autoradiography.. J Cell Biol 1 February 1976; 68 (2): 389–395. doi: https://doi.org/10.1083/jcb.68.2.389
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