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Volume 3, Issue 4
25 July 1957
Content prior to 1962 was published under the journal name
The Journal of Biophysical and Biochemical Cytology
The Journal of Biophysical and Biochemical Cytology Cover Image for Volume 3, Issue 4
Article| July 25 1957

THE EFFECTS OF FLUORIDE FEEDING ON THE ORGANIC MATRIX OF BONES AND TEETH OF PIGS AS OBSERVED BY AUTORADIOGRAPHY AFTER IN VITRO UPTAKE OF CA45 AND S35

L. F. Bélanger,
L. F. Bélanger
(From the Department of Histology and Embryology, University of Ottawa, Canada, and the Medical Division, Oak Ridge Institute of Nuclear Studies, Oak Ridge, Tennessee)
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W. J. Visek,
W. J. Visek
(From the Department of Histology and Embryology, University of Ottawa, Canada, and the Medical Division, Oak Ridge Institute of Nuclear Studies, Oak Ridge, Tennessee)
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W. E. Lotz,
W. E. Lotz
(From the Department of Histology and Embryology, University of Ottawa, Canada, and the Medical Division, Oak Ridge Institute of Nuclear Studies, Oak Ridge, Tennessee)
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C. L. Comar
C. L. Comar
(From the Department of Histology and Embryology, University of Ottawa, Canada, and the Medical Division, Oak Ridge Institute of Nuclear Studies, Oak Ridge, Tennessee)
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Author and Article Information
L. F. Bélanger
(From the Department of Histology and Embryology, University of Ottawa, Canada, and the Medical Division, Oak Ridge Institute of Nuclear Studies, Oak Ridge, Tennessee)
W. J. Visek
(From the Department of Histology and Embryology, University of Ottawa, Canada, and the Medical Division, Oak Ridge Institute of Nuclear Studies, Oak Ridge, Tennessee)
W. E. Lotz
(From the Department of Histology and Embryology, University of Ottawa, Canada, and the Medical Division, Oak Ridge Institute of Nuclear Studies, Oak Ridge, Tennessee)
C. L. Comar
(From the Department of Histology and Embryology, University of Ottawa, Canada, and the Medical Division, Oak Ridge Institute of Nuclear Studies, Oak Ridge, Tennessee)
Received: December 06 1956
Copyright, 1957, by The Rockefeller Institute for Medical Research
1957
J Biophys and Biochem Cytol (1957) 3 (4): 559–566.
https://doi.org/10.1083/jcb.3.4.559
Article history
Received:
December 06 1956

Demineralized sections of fluorinated bones and teeth have been studied by autoradiography following in vitro uptake of Ca45 or S35O4.

The portions of tissue which do not become mineralized (cartilage, prebone, predentine, and precementum) show an increased Ca45 uptake apparently related to an increase in chondroitin sulfate content in fluorosis.

The tissues from the fluoride-fed animals show an increase of in vitro uptake of sulfur in the tissues which become mineralized (bone, dentine, cementum).

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Copyright, 1957, by The Rockefeller Institute for Medical Research
1957
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