The subnucleolar structure that is involved in rDNA transcription has been controversial. A report by Koberna et al. (2002)(this issue, page 743) adds significant weight toward the idea that dense fibrillar components (DFCs)*
*
and fibrillar center (FC)/DFC borders are the sites of pre-rRNA synthesis. Abbreviations used in this paper: DFC, dense fibrillar component; FC, fibrillar center; GC, granular component; Pol I, polymerase I.
The Rockefeller University Press
2002
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