Ferritin and Imferon molecules were introduced as tracers inside "skinned" muscle fibers to test which part of the triadic junction gap is freely exchangeable with the sarcoplasm. At least 50% of the T-system surface is freely accessible from the sarcoplasm. Of the remainder, 30% of the total T-system surface is covered by the junctional feet, and 20% in the center of the junction may or may not be accessible. The possibility is discussed that the triadic junction may not function as an electrical coupling.
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Article| April 01 1971
STUDIES OF THE TRIAD : II. Penetration of Tracers into the Junctional Gap
From the Departments of Physiology and Anatomy, Duke University Medical Center, Durham, North Carolina 27706.
Dr. Franzini-Armstrong's present address is the Department of Physiology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14620
Received: July 15 1970
Revision Received: November 04 1970
Online ISSN: 1540-8140
Print ISSN: 0021-9525
Copyright © 1971 by The Rockefeller University Press
Clara Franzini-Armstrong; STUDIES OF THE TRIAD : II. Penetration of Tracers into the Junctional Gap . J Cell Biol 1 April 1971; 49 (1): 196–203. doi: https://doi.org/10.1083/jcb.49.1.196
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