THE EFFECT OF THYMIDINE ON THE DURATION OF G1 IN CHINESE HAMSTER CELLS

Tobey , R. A.; Anderson , E. C.; Petersen , D. F.

doi:10.1083/jcb.35.1.53

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Article| October 01 1967

THE EFFECT OF THYMIDINE ON THE DURATION OF G₁ IN CHINESE HAMSTER CELLS

R. A. Tobey,

R. A. Tobey

From the Biomedical Research Group, Los Alamos Scientific Laboratory, University of California, Los Alamos, New Mexico 87544

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E. C. Anderson,

E. C. Anderson

From the Biomedical Research Group, Los Alamos Scientific Laboratory, University of California, Los Alamos, New Mexico 87544

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D. F. Petersen

From the Biomedical Research Group, Los Alamos Scientific Laboratory, University of California, Los Alamos, New Mexico 87544

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Author and Article Information

R. A. Tobey

From the Biomedical Research Group, Los Alamos Scientific Laboratory, University of California, Los Alamos, New Mexico 87544

E. C. Anderson

From the Biomedical Research Group, Los Alamos Scientific Laboratory, University of California, Los Alamos, New Mexico 87544

D. F. Petersen

From the Biomedical Research Group, Los Alamos Scientific Laboratory, University of California, Los Alamos, New Mexico 87544

Received: December 27 1966

Online ISSN: 1540-8140

Print ISSN: 0021-9525

1967

J Cell Biol (1967) 35 (1): 53–59.

https://doi.org/10.1083/jcb.35.1.53

The generation time of a Chinese hamster cell line was varied by the use of different lots of sera in the culture media. Analysis of the division waves following thymidine synchronization showed that lengthening of the generation time was a result of an increase in duration of the G₁ phase and that thymidine treatment reduced the duration of G₁ back to its minimum value.

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THE EFFECT OF THYMIDINE ON THE DURATION OF G₁ IN CHINESE HAMSTER CELLS