The probable shape, size, and orientation of desmosomes of the cells comprising the secretory tubules in rat submaxillary gland was determined by statistical and algebraic methods applied to electron micrographs. It was concluded that these desmosomes are discrete ellipsoidal discs whose principal axes are in the order of 4100 and 2500 angstrom units, and that they are preferentially oriented with their long axis more or less parallel to the base-apex axis of the cell. Densitometric interpretation agrees with the statistically based reconstruction of desmosomal shape. By densitometric analysis it was also determined that the peak to peak distances between layers within these desmosomes are in essential agreement with other reported findings. The approach described may have general applications to problems in the analysis of submicroscopic morphology.
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1 July 1963
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July 01 1963
AN ANALYSIS OF DESMOSOME SHAPE, SIZE, AND ORIENTATION BY THE USE OF HISTOMETRIC AND DENSITOMETRIC METHODS WITH ELECTRON MICROSCOPY
Arnold Tamarin,
Arnold Tamarin
From the Departments of Oral Pathology and Pathology, University of Washington, Seattle
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Leo M. Sreebny
Leo M. Sreebny
From the Departments of Oral Pathology and Pathology, University of Washington, Seattle
Search for other works by this author on:
Arnold Tamarin
From the Departments of Oral Pathology and Pathology, University of Washington, Seattle
Leo M. Sreebny
From the Departments of Oral Pathology and Pathology, University of Washington, Seattle
Received:
October 22 1962
Online ISSN: 1540-8140
Print ISSN: 0021-9525
Copyright © 1963 by The Rockefeller Institute Press
1963
J Cell Biol (1963) 18 (1): 125–134.
Article history
Received:
October 22 1962
Citation
Arnold Tamarin, Leo M. Sreebny; AN ANALYSIS OF DESMOSOME SHAPE, SIZE, AND ORIENTATION BY THE USE OF HISTOMETRIC AND DENSITOMETRIC METHODS WITH ELECTRON MICROSCOPY . J Cell Biol 1 July 1963; 18 (1): 125–134. doi: https://doi.org/10.1083/jcb.18.1.125
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