The inactive X chromosome (green) visits the nucleolus (red) to maintain its inactivity.
LEE/ELSEVIER
A study in 1949 revealed that the inactive X (Xi) appeared as a nucleolar satellite in cat neurons. Despite this finding, the overwhelming impression in more recent decades has been that, in most cell types, the Xi is associated with the periphery of the nucleus, not nucleolus. The nuclear periphery, however, is also the preferred location for the active X (Xa). Using mouse embryonic stem cells, Zhang and colleagues now show that, although both Xs are often seen...
The Rockefeller University Press
2007
The Rockefeller University Press
2007
You do not currently have access to this content.