Cells overexpressing Borg3 (outlined) have long and thick septin filaments.
Macara/Macmillan
The Rho GTPase Cdc42, which has been implicated previously in cytokinesis, vesicular transport, and cell polarity, inhibits septin binding to Borgs. Macara suspects that Cdc42 may inhibit another, unknown factor that normally unfolds Borg proteins so that their septin-binding domains are exposed.
The complete disruption of septin organization...
The Rockefeller University Press
2001
The Rockefeller University Press
2001
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