PREVENTION OF PHOSPHATE - INDUCED MITOCHONDRIAL SWELLING

Kroll , Arnold J.; Kuwabara , Toichiro

doi:10.1083/jcb.15.1.29

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Article| October 01 1962

PREVENTION OF PHOSPHATE - INDUCED MITOCHONDRIAL SWELLING

Arnold J. Kroll,

Arnold J. Kroll

From the Howe Laboratory of Ophthalmology, Harvard University Medical School, Massachusetts Eye and Ear Infirmary, Boston

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Toichiro Kuwabara

From the Howe Laboratory of Ophthalmology, Harvard University Medical School, Massachusetts Eye and Ear Infirmary, Boston

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Author and Article Information

Arnold J. Kroll

From the Howe Laboratory of Ophthalmology, Harvard University Medical School, Massachusetts Eye and Ear Infirmary, Boston

Toichiro Kuwabara

From the Howe Laboratory of Ophthalmology, Harvard University Medical School, Massachusetts Eye and Ear Infirmary, Boston

Received: April 09 1962

Online ISSN: 1540-8140

Print ISSN: 0021-9525

Copyright, 1962, by The Rockefeller Institute Press

1962

J Cell Biol (1962) 15 (1): 29–35.

https://doi.org/10.1083/jcb.15.1.29

The prevention of phosphate-induced mitochondrial swelling in the whole retina of the rabbit was studied with the electron microscope. It was found that a mixture of ATP, Mg⁺⁺, and bovine serum albumin protected the mitochondria in vitro. This finding confirmed the results obtained spectrophotometrically with isolated rat liver mitochondria by Lehninger.

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Copyright, 1962, by The Rockefeller Institute Press

1962

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