The Year in Cell Biology: 2025
Our annual collection highlights 13 of the year's most impactful papers that have garnered exceptional interest from our readership.
The collection features new advances in plasma membrane repair, autophagy, protein homeostasis, and organelle-dependent cell signaling. It explores mechanisms underlying the phagocytic fate of epithelial cells as well as the interplay between lysosomal exocytosis and focal adhesions. It presents a new meiosis-specific organelle and introduces valuable resources such as a proteome-wide yeast degron library. Additional highlights include discoveries on how sphingolipid metabolism regulates stem cell homeostasis and how mitochondrial dynamics affect astrocyte morphogenesis.
JCB is proud to continue publishing high-quality research. We are grateful that scientists regard our journal as a leading venue for their groundbreaking discoveries as well as for our reviewers’ and readers’ support and enthusiasm. We reflect on a year of cutting-edge findings, spanning the diverse spectrum of cell biology, and look forward to a new year of transformative research ahead.
Find the original research articles below and download a special magazine that contains the abstracts of ten of the studies featured in the collection.
We welcome your feedback on X/Twitter at @JCellBiol and Bluesky at @jcb.org. Sign up to receive notifications about future special collections here.
Original artwork by Bianca Dunn
